Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor. - Wikidata - awgldk - TriplyDB

Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.

Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.

http://www.wikidata.org/entity/Q34479025

about

Synthetic LXR ligand inhibits the development of atherosclerosis in mice The retinoid X receptors and their ligands MicroRNAs in lipid metabolism Regulation of the nongenomic actions of retinoid X receptor-α by targeting the coregulator-binding sites Cholesterol, inflammation and innate immunity Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets Is it time to modify the reverse cholesterol transport model?Cloning of a novel retinoid-inducible serine carboxypeptidase from vascular smooth muscle cells PDGF-induced proliferation of smooth muscular cells is related to the regulation of CREB phosphorylation and Nur77 expression Glucose regulates LXRalpha subcellular localization and function in rat pancreatic beta-cells Macrophage-independent regulation of reverse cholesterol transport by liver X receptors.PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells.Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia.Thiazolidinedione-independent activation of peroxisome proliferator-activated receptor γ is a potential target for diabetic macrovascular complications.Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver.Nuclear receptors, mitochondria and lipid metabolism Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligand CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridemia, hepatomegaly and body weight gain in animal models.Identification of macrophage liver X receptors as inhibitors of atherosclerosis.Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.Retinaldehyde dehydrogenase 1 deficiency inhibits PPARγ-mediated bone loss and marrow adiposity.Novel agents for managing dyslipidaemia.Effect of a peroxisome proliferator-activated receptor-gamma agonist on myocardial blood flow in type 2 diabetes Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions Regulation and mechanisms of macrophage cholesterol efflux The macrophage foam cell as a target for therapeutic intervention.RXR activators molecular signalling: involvement of a PPAR alpha-dependent pathway in the liver and kidney, evidence for an alternative pathway in the heart Retinoids: fascinating up-and-coming scenario.PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity.Actions of calcium channel blockers on vascular proteoglycan synthesis: relationship to atherosclerosis.Peroxisome proliferator-activated receptor gamma: the more the merrier?End-stage renal disease--not an equal opportunity disease: the role of genetic polymorphisms.Combinatorial roles of nuclear receptors in inflammation and immunity.The vascular biology of peroxisome proliferator-activated receptors: modulation of atherosclerosis Transcriptional Control of Vascular Smooth Muscle Cell Proliferation by Peroxisome Proliferator-Activated Receptor-gamma: Therapeutic Implications for Cardiovascular Diseases.PPAR Agonists and Cardiovascular Disease in Diabetes.

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P2860

Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.

http://www.wikidata.org/entity/Q34479025

description

2001 nî lūn-bûn

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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2001 թվականի փետրվարին հրատարակված գիտական հոդված

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2001年の論文

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Reduction of atherosclerosis i ...... on of the retinoid X receptor.

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Reduction of atherosclerosis i ...... on of the retinoid X receptor.

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Reduction of atherosclerosis i ...... on of the retinoid X receptor.

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Reduction of atherosclerosis i ...... on of the retinoid X receptor.

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Reduction of atherosclerosis i ...... on of the retinoid X receptor.

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Proceedings of the National Academy of Sciences of the United States of America

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Reduction of atherosclerosis i ...... ion of the retinoid X receptor

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B Wagner

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C Fiévet

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G Torpier

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J Auwerx

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J J Repa

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J M Lobaccaro

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J R Paterniti

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M D Leibowitz

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R A Heyman

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T Claudel

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P2860

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

The RXR heterodimers and orphan receptors

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

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2610-2615

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10.1073/PNAS.041609298

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5

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98

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David J Mangelsdorf

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2001-02-20T00:00:00Z

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12105766

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11226287

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atherosclerosis

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30186

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