Lipophosphoglycan of the protozoan parasite Leishmania: stage- and species-specific importance for colonization of the sandfly vector, transmission and virulence to mammals.
about
Identification of genes encoding arabinosyltransferases (SCA) mediating developmental modifications of lipophosphoglycan required for sand fly transmission of leishmania major.Leishmania major glycosylation mutants require phosphoglycans (lpg2-) but not lipophosphoglycan (lpg1-) for survival in permissive sand fly vectors.Identifying vaccine targets for anti-leishmanial vaccine developmentThe N-terminal domain and glycosomal localization of Leishmania initial acyltransferase LmDAT are important for lipophosphoglycan synthesisLeishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viabilityProtozomics: trypanosomatid parasite genetics comes of age.The role(s) of lipophosphoglycan (LPG) in the establishment of Leishmania major infections in mammalian hosts.Leishmania dihydroxyacetonephosphate acyltransferase LmDAT is important for ether lipid biosynthesis but not for the integrity of detergent resistant membranes.Innate immune activation and subversion of Mammalian functions by leishmania lipophosphoglycan.Leishmania cell wall as a potent target for antiparasitic drugs. A focus on the glycoconjugates.Leishmania major expresses a single dihydroxyacetone phosphate acyltransferase localized in the glycosome, important for rapid growth and survival at high cell density and essential for virulence.Functional identification of galactosyltransferases (SCGs) required for species-specific modifications of the lipophosphoglycan adhesin controlling Leishmania major-sand fly interactions.
P2860
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P2860
Lipophosphoglycan of the protozoan parasite Leishmania: stage- and species-specific importance for colonization of the sandfly vector, transmission and virulence to mammals.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@ast
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@en
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@nl
type
label
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@ast
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@en
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@nl
prefLabel
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@ast
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@en
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@nl
P356
P1476
Lipophosphoglycan of the proto ...... sion and virulence to mammals.
@en
P2093
P2888
P356
10.1007/S004300100071
P577
2001-11-01T00:00:00Z
P6179
1005645978