Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion. - Wikidata - awgldk - TriplyDB

Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.

Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.

http://www.wikidata.org/entity/Q34480114

about

Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor The differential expression of IL-4 and IL-13 and its impact on type-2 immunity Multifaceted roles of cysteinyl leukotrienes in eliciting eosinophil granule protein secretion Pulmonary instillation of MWCNT increases lung permeability, decreases gp130 expression in the lungs, and initiates cardiovascular IL-6 transsignaling Factors driving the aspirin exacerbated respiratory disease phenotype.Prominent role of IFN-γ in patients with aspirin-exacerbated respiratory disease.Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha.Eosinophil granules function extracellularly as receptor-mediated secretory organelles Eosinophils in Autoimmune Diseases.Cysteinyl leukotrienes acting via granule membrane-expressed receptors elicit secretion from within cell-free human eosinophil granules.Human eosinophils recognize endogenous danger signal crystalline uric acid and produce proinflammatory cytokines mediated by autocrine ATP.IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro.Pre-embedding immunogold labeling to optimize protein localization at subcellular compartments and membrane microdomains of leukocytes.Eosinophil secretion of granule-derived cytokines.Eosinophil cytokines, chemokines, and growth factors: emerging roles in immunity.Eosinophils: offenders or general bystanders in allergic airway disease and pulmonary immunity?Eosinophils: changing perspectives in health and disease.Schistosoma mansoni infection in eosinophil lineage-ablated mice.Expression and subcellular localization of the Qa-SNARE syntaxin17 in human eosinophils.Eosinophil crystalloid granules: structure, function, and beyond.Contributions of electron microscopy to understand secretion of immune mediators by human eosinophils.Piecemeal degranulation in human eosinophils: a distinct secretion mechanism underlying inflammatory responses Differential secretion of cytokines.Eosinophils in vasculitis: characteristics and roles in pathogenesis.Eosinophils in innate immunity: an evolving story.Electron tomography and immunonanogold electron microscopy for investigating intracellular trafficking and secretion in human eosinophils.Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteins Human eosinophils express functional CCR7.Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation.Subcellular fractionation of human eosinophils: isolation of functional specific granules on isoosmotic density gradients An essential role for Rab27a GTPase in eosinophil exocytosis.Pivotal advance: eosinophils mediate early alum adjuvant-elicited B cell priming and IgM production.Extracellular Microvesicle Production by Human Eosinophils Activated by "Inflammatory" Stimuli.Functional extracellular eosinophil granules: novel implications in eosinophil immunobiology.Eosinophil activities modulate the immune/inflammatory character of allergic respiratory responses in mice.NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: a link between innate immunity and allergic asthma.Pathways for cytokine secretion.Eosinophil-derived cytokines in health and disease: unraveling novel mechanisms of selective secretion.The Eosinophil in Health and Disease: from Bench to Bedside and Back.

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P2860

Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.

http://www.wikidata.org/entity/Q34480114

description

2006 nî lūn-bûn

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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2006年の論文

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Cytokine receptor-mediated tra ...... chanism of cytokine secretion.

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Cytokine receptor-mediated tra ...... chanism of cytokine secretion.

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Cytokine receptor-mediated tra ...... chanism of cytokine secretion.

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Proceedings of the National Academy of Sciences of the United States of America

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Cytokine receptor-mediated tra ...... echanism of cytokine secretion

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Ann M Dvorak

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Lisa A Spencer

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Peter F Weller

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Sandra A C Perez

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Staci P Bafford

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P2860

Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexes

Human eosinophils express and release IL-13 following CD28-dependent activation

A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha -2 and their rapid mobilization by interferon-gamma

Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments.

Rapid mobilization of intracellularly stored RANTES in response to interferon-gamma in human eosinophils.

Intracellular localization of interleukin-6 in eosinophils from atopic asthmatics and effects of interferon gamma.

Neutrophil-derived proteins: selling cytokines by the pound.

Mechanisms of eosinophil-associated inflammation.

Eosinophil cytokines.

Degranulation patterns of eosinophil granulocytes as determinants of eosinophil driven disease.

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