Activity-dependent FUS dysregulation disrupts synaptic homeostasis - Wikidata - awgldk - TriplyDB

Activity-dependent FUS dysregulation disrupts synaptic homeostasis

Activity-dependent FUS dysregulation disrupts synaptic homeostasis

http://www.wikidata.org/entity/Q34480824

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From animal models to human disease: a genetic approach for personalized medicine in ALS Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis Modeling ALS and FTD with iPSC-derived neurons The function of RNA-binding proteins at the synapse: implications for neurodegeneration Pathogenesis of FUS-associated ALS and FTD: insights from rodent models Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.Altered mRNP granule dynamics in FTLD pathogenesis.Rodent Models of Amyotrophic Lateral Sclerosis Severe respiratory changes at end stage in a FUS-induced disease state in adult rats.Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons.ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function.Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4.FUS Mislocalization and Vulnerability to DNA Damage in ALS Patients Derived hiPSCs and Aging Motoneurons.Sequestration of PRMT1 and Nd1-L mRNA into ALS-linked FUS mutant R521C-positive aggregates contributes to neurite degeneration upon oxidative stress.Pushing the threshold: How NMDAR antagonists induce homeostasis through protein synthesis to remedy depression.ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.Clinical and experimental studies of a novel P525R FUS mutation in amyotrophic lateral sclerosis.Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS.Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice.Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis.Role of the visual experience-dependent nascent proteome in neuronal plasticity.Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD.Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions.Importance of Functional Loss of FUS in FTLD/ALS.RNA-Binding Proteins in Amyotrophic Lateral Sclerosis From Mouse Models to Human Disease: An Approach for Amyotrophic Lateral Sclerosis

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

http://www.wikidata.org/entity/Q34480824

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

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2014年論文

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2014年论文

@wuu

name

Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

@nl

type

label

Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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prefLabel

Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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PNAS.1406162111

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Proceedings of the National Academy of Sciences of the United States of America

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Activity-dependent FUS dysregulation disrupts synaptic homeostasis

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Amy A Tang

http://www.w3.org/2001/XMLSchema#string

Ashwinikumar Kulkarni

http://www.w3.org/2001/XMLSchema#string

Carla B Green

http://www.w3.org/2001/XMLSchema#string

Chantelle F Sephton

http://www.w3.org/2001/XMLSchema#string

Gang Yu

http://www.w3.org/2001/XMLSchema#string

James West

http://www.w3.org/2001/XMLSchema#string

Jeremy J Stubblefield

http://www.w3.org/2001/XMLSchema#string

Joachim Herz

http://www.w3.org/2001/XMLSchema#string

Kimberly M Huber

http://www.w3.org/2001/XMLSchema#string

Michael Q Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Dendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons.

Rules for nuclear localization sequence recognition by karyopherin beta 2

FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration

Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)

Conserved structures and diversity of functions of RNA-binding proteins

Identification of an RNA binding specificity for the potential splicing factor TLS

Proteomic analysis of NMDA receptor-adhesion protein signaling complexes

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

Domain architectures and characterization of an RNA-binding protein, TLS

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