Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.
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New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncologyThe evolutionary portrait of metazoan NAD salvageExtracellular nicotinamide phosphoribosyltransferase, a new cancer metabokineStructural basis for resistance to diverse classes of NAMPT inhibitorsIdentification of novel pathogenic copy number aberrations in multiple myeloma: the Malaysian contextNext-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.Discovery and characterization of novel small-molecule inhibitors targeting nicotinamide phosphoribosyltransferaseThe c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors.Recycling nicotinamide. The transition-state structure of human nicotinamide phosphoribosyltransferase.PBEF/NAMPT/visfatin: a promising drug target for treating rheumatoid arthritis?The Role of Nicotinamide Phosphoribosyltransferase in Cerebral Ischemia.Physiological and pathophysiological roles of NAMPT and NAD metabolism.Inhibition of nicotinamide phosphoribosyltransferase and depletion of nicotinamide adenine dinucleotide contribute to arsenic trioxide suppression of oral squamous cell carcinoma.Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin.Expression patterns of nicotinamide phosphoribosyltransferase and nicotinic acid phosphoribosyltransferase in human malignant lymphomas.Oligo-carrageenan kappa increases NADPH, ascorbate and glutathione syntheses and TRR/TRX activities enhancing photosynthesis, basal metabolism, and growth in Eucalyptus trees.NAMPT is the cellular target of STF-31-like small-molecule probes.Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia.Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA.Cross resistance to diverse anticancer nicotinamide phosphoribosyltransferase inhibitors induced by FK866 treatment.
P2860
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P2860
Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@ast
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@en
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@nl
type
label
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@ast
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@en
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@nl
prefLabel
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@ast
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@en
Target enzyme mutations are th ...... ide phosphoribosyltransferase.
@nl
P2093
P2860
P50
P356
P1433
P1476
Target enzyme mutations are th ...... mide phosphoribosyltransferase
@en
P2093
Antje Garten
Jakob G Petersen
Jun Yoshino
Maxwell Sehested
Mette K Christensen
Peter B Jensen
Shin-Ichiro Imai
Søren J Nielsen
Wieland Kiess
P2860
P2888
P356
10.1186/1471-2407-10-677
P407
P577
2010-12-12T00:00:00Z
P5875
P6179
1029764717