A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer.
about
Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo.PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis.The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention.Protein kinase A-dependent phosphorylation of Rap1 regulates its membrane localization and cell migrationEPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer.Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Vascular Endothelial Growth Factor-A Exerts Diverse Cellular Effects via Small G Proteins, Rho and Rap.
P2860
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P2860
A novel interplay between Rap1 and PKA regulates induction of angiogenesis in prostate cancer.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@ast
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@en
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@nl
type
label
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@ast
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@en
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@nl
prefLabel
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@ast
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@en
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@nl
P2093
P2860
P1433
P1476
A novel interplay between Rap1 ...... giogenesis in prostate cancer.
@en
P2093
Elena Bevilacqua
Jyotsana Menon
Katie M Reindl
Marsha Rich Rosner
Robert C Doebele
Suzana Gomes
P2860
P304
P356
10.1371/JOURNAL.PONE.0049893
P407
P577
2012-11-15T00:00:00Z