Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage
about
Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety AssessmentLongitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor.The human toxome projectContributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents.p53 induction and cell viability modulation by genotoxic individual chemicals and mixtures.Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells.Pathway Based Toxicology and Fit-for-Purpose Assays.Rational Design of Ruthenium Complexes Containing 2,6-Bis(benzimidazolyl)pyridine Derivatives with Radiosensitization Activity by Enhancing p53 Activation.Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats.Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation.Contribution of ATM and ATR kinase pathways to p53-mediated response in etoposide and methyl methanesulfonate induced DNA damage.Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro.A Qualitative Modeling Approach for Whole Genome Prediction Using High-Throughput Toxicogenomics Data and Pathway-Based ValidationBridging the Data Gap From Toxicity Testing to Chemical Safety Assessment Through Computational Modeling
P2860
Q28383566-A01241C4-8024-4404-84E3-94CD38C2597BQ30665952-B2668B10-ABAC-4FAD-A2D3-CC718AFA7561Q34465807-DB5F488E-CBF6-4CC6-A6BE-A1776CB2E539Q36759955-371A4156-E059-4265-BBD4-69B427D6BF2CQ38711897-E4DF2E37-210A-430B-A7B0-4EFC92E79DB5Q38806892-B6196688-1821-42F7-B3F2-8EA8CD67E3F2Q39348556-2FB370FC-34D9-49B8-9471-24878C30F79DQ46737262-0A2B227F-2D03-4858-AA78-7AA951AC4B7DQ50769278-116B5376-6257-4864-AA4A-1CD9A6514333Q50886844-BBECA5D1-9D40-46E2-ADA2-F51CA4BA557AQ51138491-D3BC940A-CF5C-430E-80A6-5487B6D22C52Q52886000-2ED5A3B5-F8AF-46BF-8E21-9189F896CFDCQ58586925-C1A5A3C4-9FD4-4733-B763-A3FF3774FF00Q58750452-7C16C117-CCA7-496B-939B-0DB0D0DF4822
P2860
Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@ast
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@en
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@nl
type
label
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@ast
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@en
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@nl
prefLabel
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@ast
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@en
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@nl
P2093
P2860
P356
P1476
Profiling dose-dependent activ ...... tinct mechanisms of DNA damage
@en
P2093
Alina Efremenko
Andy White
Patrick D McMullen
Paul Carmichael
Rebecca A Clewell
Salil Pendse
Yeyejide Adeleye
P2860
P356
10.1093/TOXSCI/KFU153
P577
2014-07-30T00:00:00Z