Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice - Wikidata - awgldk - TriplyDB

Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice

Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice

http://www.wikidata.org/entity/Q34485920

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Selective Insulin Resistance in the Kidney Targeting inflammation in diabetes: Newer therapeutic options Lipids and the endothelium: bidirectional interactions Inflammation and oxidative stress in diabetic nephropathy: new insights on its inhibition as new therapeutic targets The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases Insulin resistance, hyperglycemia, and atherosclerosis Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR) Regulates Lipolysis in White Adipocytes via the PTEN/AKT Signaling Pathway Ceacam1 deletion causes vascular alterations in large vessels Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells Insulin Enhances Endothelial Function Throughout the Arterial Tree in Healthy But Not Metabolic Syndrome Subjects.Variation in Type 2 Diabetes-Related Phenotypes among Apolipoprotein E-Deficient Mouse Strains Vascular function, insulin action, and exercise: an intricate interplay The endothelial cell: an "early responder" in the development of insulin resistance.Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1 Insulin regulates its own delivery to skeletal muscle by feed-forward actions on the vasculature.WNT5A-JNK regulation of vascular insulin resistance in human obesity.Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models into disease mechanisms.Effect of PIP3 on adhesion molecules and adhesion of THP-1 monocytes to HUVEC treated with high glucose Modulating Notch signaling to enhance neovascularization and reperfusion in diabetic mice.Lipotoxicity contributes to endothelial dysfunction: a focus on the contribution from ceramide.Enhanced inflammatory responses to toll-like receptor 2/4 stimulation in type 1 diabetic coronary artery endothelial cells: the effect of insulin Parental history of type 2 diabetes, TCF7L2 variant and lower insulin secretion are associated with incident hypertension. Data from the DESIR and RISC cohorts.Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis.PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.Urinary miR-29 correlates with albuminuria and carotid intima-media thickness in type 2 diabetes patients.Protein kinase C inhibition ameliorates functional endothelial insulin resistance and vascular smooth muscle cell hypersensitivity to insulin in diabetic hypertensive rats Role of oxidative stress in endothelial insulin resistance.Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis.Inhibition of insulin signaling in endothelial cells by protein kinase C-induced phosphorylation of p85 subunit of phosphatidylinositol 3-kinase (PI3K).Vascular effects of exercise: endothelial adaptations beyond active muscle beds FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis.Insulin resistance, metabolic stress, and atherosclerosis.Uncomplicating the Macrovascular Complications of Diabetes: The 2014 Edwin Bierman Award Lecture Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene.Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice.Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells.Microvascular management of systemic insulin sensitivity.Mechanisms of lipotoxicity in the cardiovascular system.Role of habitual physical activity in modulating vascular actions of insulin.Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance.

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P2860

Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice

http://www.wikidata.org/entity/Q34485920

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2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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J.CMET.2010.03.013

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Cell Metabolism

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Loss of insulin signaling in v ...... in apolipoprotein E null mice

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Allen Clermont

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Amy J Wagers

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Bryn Freund

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C Ronald Kahn

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Christian Rask-Madsen

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Claudia Dall'Osso

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Danielle Feather

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George L King

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I-Hsien Wu

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Jan Goldenbogen

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P2860

Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide

Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.

Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats.

Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release

Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation.

The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance.

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses.

Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes.

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10.1016/J.CMET.2010.03.013

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44575025

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20444418

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atherosclerosis

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3020149

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