Plasma membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes interleukin-6-induced apoptosis suppression and cell motility.
about
Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunitReduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidaseA meta-analysis of kidney microarray datasets: investigation of cytokine gene detection and correlation with rt-PCR and detection thresholdsModerate strength (0.23-0.28 T) static magnetic fields (SMF) modulate signaling and differentiation in human embryonic cellsRegulation of intracellular signaling by extracellular glycan remodeling.Accumulation of long-chain glycosphingolipids during aging is prevented by caloric restriction.LPS-induced cytokine production in human dendritic cells is regulated by sialidase activitySialoside-based pattern recognitions discriminating infections from tissue injuries.Increased sialidase activity in serum of cancer patients: Identification of sialidase and inhibitor activities in human serumPotentiation of epidermal growth factor-mediated oncogenic transformation by sialidase NEU3 leading to Src activation.Plasma membrane-associated sialidase (NEU3) regulates progression of prostate cancer to androgen-independent growth through modulation of androgen receptor signalingUpregulation of sialidase NEU3 in head and neck squamous cell carcinoma associated with lymph node metastasis.Modulation of cell functions by glycosphingolipid metabolic remodeling in the plasma membrane.Aberrant expression of sialidase and cancer progression.Developmental change of sialidase neu4 expression in murine brain and its involvement in the regulation of neuronal cell differentiationRegulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis.Fine tuning of cell functions through remodeling of glycosphingolipids by plasma membrane-associated glycohydrolases.Remodeling of sphingolipids by plasma membrane associated enzymes.Sialidase significance for cancer progression.The glycosphingolipid hydrolases in the central nervous system.GM3 and cancer.Sialic acids in cancer biology and immunity.The plasma membrane sialidase NEU3 regulates the malignancy of renal carcinoma cells by controlling β1 integrin internalization and recycling.Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides.Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU4.Overexpression of Csk-binding protein contributes to renal cell carcinogenesis.NEU3 sialidase strictly modulates GM3 levels in skeletal myoblasts C2C12 thus favoring their differentiation and protecting them from apoptosis.Role of Neu4L sialidase and its substrate ganglioside GD3 in neuronal apoptosis induced by catechol metabolites.NEU3 Sialidase Protein Interactors in the Plasma Membrane and in the Endosomes.Sialidase NEU3 is a peripheral membrane protein localized on the cell surface and in endosomal structures.Molecular cloning and biochemical characterization of medaka (Oryzias latipes) lysosomal neu4 sialidase.Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells.Identification of potential pathogenic biomarkers in clear cell renal cell carcinoma.Serum sialylation changes in cancer.
P2860
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P2860
Plasma membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes interleukin-6-induced apoptosis suppression and cell motility.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Plasma membrane-associated sia ...... suppression and cell motility.
@ast
Plasma membrane-associated sia ...... suppression and cell motility.
@en
Plasma membrane-associated sia ...... suppression and cell motility.
@nl
type
label
Plasma membrane-associated sia ...... suppression and cell motility.
@ast
Plasma membrane-associated sia ...... suppression and cell motility.
@en
Plasma membrane-associated sia ...... suppression and cell motility.
@nl
prefLabel
Plasma membrane-associated sia ...... suppression and cell motility.
@ast
Plasma membrane-associated sia ...... suppression and cell motility.
@en
Plasma membrane-associated sia ...... suppression and cell motility.
@nl
P2093
P356
P1476
Plasma membrane-associated sia ...... suppression and cell motility.
@en
P2093
Kazunori Yamaguchi
Makoto Satoh
Seiichi Saito
Seiji Ueno
Tadashi Wada
Taeko Miyagi
Yoichi Arai
P304
P356
10.1074/JBC.M509668200
P407
P577
2006-01-20T00:00:00Z