Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties.
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Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous systemAmiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptorsNovel Insights into Acid-Sensing Ion Channels: Implications for Degenerative DiseasesStructure and activity of the acid-sensing ion channelsThe epithelial sodium channel δ-subunit: new notes for an old songTwo aspects of ASIC function: Synaptic plasticity and neuronal injury.Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neuronsUp-regulation of acid-gated Na(+) channels (ASICs) by cystic fibrosis transmembrane conductance regulator co-expression in Xenopus oocytesPSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated currentAcid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neuronsASIC2a and ASIC3 heteromultimerize to form pH-sensitive channels in mouse cardiac dorsal root ganglia neuronsKnockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearingExpressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioningThe Concise Guide to PHARMACOLOGY 2013/14: ion channelsAcid-sensing ion channels in mouse olfactory bulb M/T neurons.Functional domains within the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels.Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels.Acid-sensing ion channels in acidosis-induced injury of human brain neuronsDistinct subclassification of DRG neurons innervating the distal colon and glans penis/distal urethra based on the electrophysiological current signature.ASIC1 and ASIC3 play different roles in the development of Hyperalgesia after inflammatory muscle injury.Distribution and functional properties of human KCNH8 (Elk1) potassium channels.Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant.ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domainInterregulation of proton-gated Na(+) channel 3 and cystic fibrosis transmembrane conductance regulator.Acid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damageEffect of carbon dioxide on calcitonin gene-related peptide secretion from trigeminal neurons.Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride.ENaCs and ASICs as therapeutic targets.Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567ASIC3 channels in multimodal sensory perceptionHuman ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions.ASIC subunit ratio and differential surface trafficking in the brain.ASIC proteins regulate smooth muscle cell migration.The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization.Conformational changes associated with proton-dependent gating of ASIC1a.A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons.Calcium-permeable ion channels in pain signaling.Translational strategies for neuroprotection in ischemic stroke--focusing on acid-sensing ion channel 1a.Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?
P2860
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P2860
Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Molecular cloning and regional ...... iphasic functional properties.
@ast
Molecular cloning and regional ...... iphasic functional properties.
@en
Molecular cloning and regional ...... iphasic functional properties.
@nl
type
label
Molecular cloning and regional ...... iphasic functional properties.
@ast
Molecular cloning and regional ...... iphasic functional properties.
@en
Molecular cloning and regional ...... iphasic functional properties.
@nl
prefLabel
Molecular cloning and regional ...... iphasic functional properties.
@ast
Molecular cloning and regional ...... iphasic functional properties.
@en
Molecular cloning and regional ...... iphasic functional properties.
@nl
P2093
P2860
P1476
Molecular cloning and regional ...... iphasic functional properties.
@en
P2093
P2860
P356
10.1046/J.1471-4159.1999.0720051.X
P407
P577
1999-01-01T00:00:00Z