Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria

Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria

Item
http://www.wikidata.org/entity/Q34492813
Liver accumulation of Plasmodium chabaudi-infected red blood cells and modulation of regulatory T cell and dendritic cell responsesDelivery of large heterologous polypeptides across the cytoplasmic membrane of antigen-presenting cells by the Bordetella RTX hemolysin moiety lacking the adenylyl cyclase domain.Depletion of regulatory T cells augments a vaccine-induced T effector cell response against the liver-stage of malaria but fails to increase memory.Plasmodium berghei circumsporozoite protein encapsulated in oligomannose-coated liposomes confers protection against sporozoite infection in mice.Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells.Adenylate cyclase toxin-hemolysin relevance for pertussis vaccines.Nematode-induced interference with the anti-Plasmodium CD8+ T-cell response can be overcome by optimizing antigen administration.Plasmodium berghei sporozoite challenge of vaccinated BALB/c mice leads to the induction of humoral immunity and improved function of CD8(+) memory T cells.Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin.Both CD4⁺ and CD8⁺ lymphocytes participate in the IFN-γ response to filamentous hemagglutinin from Bordetella pertussis in infants, children, and adults.
P2860

Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria

Item
http://www.wikidata.org/entity/Q34492813
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Immunization with a circumspor ...... um berghei liver-stage malaria
@ast
Immunization with a circumspor ...... um berghei liver-stage malaria
@en
Immunization with a circumspor ...... um berghei liver-stage malaria
@nl
type
label
Immunization with a circumspor ...... um berghei liver-stage malaria
@ast
Immunization with a circumspor ...... um berghei liver-stage malaria
@en
Immunization with a circumspor ...... um berghei liver-stage malaria
@nl
prefLabel
Immunization with a circumspor ...... um berghei liver-stage malaria
@ast
Immunization with a circumspor ...... um berghei liver-stage malaria
@en
Immunization with a circumspor ...... um berghei liver-stage malaria
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Immunization with a circumspor ...... um berghei liver-stage malaria
@en
P2093
P2860
P304
P31
P356
10.1128/IAI.74.4.2277-2285.2006
P407
P433
P478
P50
P577
P698
P921
P932