Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication - Wikidata - awgldk - TriplyDB

Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication

Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication

http://www.wikidata.org/entity/Q34497765

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Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells Probing disorders of the nervous system using reprogramming approaches.Up-regulation of SNCA gene expression: implications to synucleinopathies Advancing drug discovery for neuropsychiatric disorders using patient-specific stem cell models.Mechanisms of alpha-synuclein action on neurotransmission: cell-autonomous and non-cell autonomous role Structural variants in SNCA gene and the implication to synucleinopathies.The rs3857059 variant of the SNCA gene is associated with Parkinson's disease in Mexican Mestizos.Multisystem Lewy body disease and the other parkinsonian disorders.Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein?Characterization of a Novel Mutation in SLC1A1 Associated with Schizophrenia.Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson's Disease.Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons.The genetic architecture of mitochondrial dysfunction in Parkinson's disease.β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease.Modeling Parkinson's disease with induced pluripotent stem cells harboring α-synuclein mutations.Advancing Stem Cell Models of Alpha-Synuclein Gene Regulation in Neurodegenerative Disease.α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.Modeling Parkinson's Disease Using Patient-specific Induced Pluripotent Stem Cells Synaptic dysfunction in neurodegenerative and neurodevelopmental diseases: an overview of induced pluripotent stem-cell-based disease models

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Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication

http://www.wikidata.org/entity/Q34497765

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2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2014年の論文

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2014年論文

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2014年論文

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Higher vulnerability and stres ...... ha-synuclein gene triplication

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Higher vulnerability and stres ...... ha-synuclein gene triplication

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Higher vulnerability and stres ...... ha-synuclein gene triplication

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Higher vulnerability and stres ...... ha-synuclein gene triplication

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Adrian Flierl

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Birgitt Schüle

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Donna J Arndt-Jovin

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Frank Soldner

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J William Langston

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Jayne Hesley

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Rudolf Jaenisch

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Sally K Mak

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Thomas M Jovin

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P2860

Rotenone, paraquat, and Parkinson's disease

NIH Image to ImageJ: 25 years of image analysis

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

The endoplasmic reticulum stress response in aging and age-related diseases

Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.

MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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e112413

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Luís M. A. Oliveira

Lisandro J. Falomir Lockhart

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2014-11-12T00:00:00Z

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268232441

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