Uncovering the molecular mode of action of the antimalarial drug atovaquone using a bacterial system.
about
Molecular mechanisms of superoxide production by complex III: a bacterial versus human mitochondrial comparative case studyMutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone AntimalarialsThe suf iron-sulfur cluster synthesis pathway is required for apicoplast maintenance in malaria parasitesMuddled mechanisms: recent progress towards antimalarial target identificationReconstructing the Qo site of Plasmodium falciparum bc 1 complex in the yeast enzymeSubnanomolar inhibitor of cytochrome bc1 complex designed by optimizing interaction with conformationally flexible residuesMetabolic fate of fumarate, a side product of the purine salvage pathway in the intraerythrocytic stages of Plasmodium falciparum.Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy.2,3-diphenyl-1,4-naphthoquinone: a potential chemotherapeutic agent against Trypanosoma cruzi.Plasmodium drug targets outside the genetic control of the parasite.Loss of a conserved tyrosine residue of cytochrome b induces reactive oxygen species production by cytochrome bc1.Molecular surveillance of mutations in the cytochrome b gene of Plasmodium falciparum in Gabon and Ethiopia.Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain functionA chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitorTyrosine triad at the interface between the Rieske iron-sulfur protein, cytochrome c1 and cytochrome c2 in the bc1 complex of Rhodobacter capsulatus.Drug-resistant malaria - an insight.Pyrimidine Pathway-Dependent and -Independent Functions of the Toxoplasma gondii Mitochondrial Dihydroorotate Dehydrogenase.Repurposing atovaquone: targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells.Antimalarial drugs: modes of action and mechanisms of parasite resistance.Novel antimalarial drug targets: hope for new antimalarial drugs.A drug-selected Plasmodium falciparum lacking the need for conventional electron transportHuman Mitochondrial Cytochrome b Variants Studied in Yeast: Not All Are Silent Polymorphisms.Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.Probing binding determinants in center P of the cytochrome bc(1) complex using novel hydroxy-naphthoquinonesAntiplasmodial activity of [(aryl)arylsulfanylmethyl]Pyridine.Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum.Anti-malarial atovaquone exhibits anti-tumor effects by inducing DNA damage in hepatocellular carcinoma
P2860
Q26825065-E795FCA5-3092-4178-866D-B58C06AE21B5Q27861952-13271F13-9DF1-411B-B47F-62DCF41C00E4Q27974759-45D9A129-5162-490A-BA98-BF0E823E775AQ28066421-F0F7C22B-897D-4314-83DA-8EC96064162FQ28535248-B5799F5F-68C2-4BFA-8202-3F837E6943BFQ33606046-8AB4B461-671E-4E04-A597-6A6B2319FE50Q33786498-A63EFBE7-ABC9-4C36-AD5B-898B4D5B7062Q33903812-36CF3703-F95D-4823-98A8-31968FBC79A2Q34090268-12AD8137-4C52-4EDC-A4DD-9C18FB2C0D27Q34678568-AB8FBB06-434F-4825-AB27-2E4343BD499CQ34979090-0B29984C-384C-4C2E-A53E-563C74174EBAQ35191258-1248F337-2343-44A2-A6BC-B60420D48524Q35191792-DCF1FD7A-872A-45F3-98FE-E17AA11FCA41Q35563452-FCC9C081-B3F8-4E65-B4FA-14A612E8CA92Q35877970-047236AC-18F9-4F32-8DF0-D59FA4A65976Q36933785-FEA680D3-8437-45AE-9986-5F860DC859A8Q37287221-C85016CA-8A45-4836-B1B0-93528FC76CF9Q37376205-4F730EFB-6E0B-4618-8807-4EA31B65CBEDQ37820670-04BB2911-8236-4A2E-8E14-FE1A24A651EEQ37960187-F5163BEE-F03D-42AA-98C0-238979345579Q38622216-6783046B-0ABB-4F3A-BDE5-69BB43366880Q38854421-463CB96A-5D12-491D-A71A-AA9C26C82C28Q39306287-802336FD-E622-453B-B175-7A46ED55DC62Q41767081-9AE52772-0041-4EB9-8811-8C43E373D042Q41886196-AAB43682-3B19-4478-9899-1826D2EDE207Q47964175-0F767AEB-A2B2-4D13-8596-008B138BBB12Q57494137-BBBB02E5-A20E-43F5-BF6E-CDBDFA50453A
P2860
Uncovering the molecular mode of action of the antimalarial drug atovaquone using a bacterial system.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Uncovering the molecular mode ...... uone using a bacterial system.
@ast
Uncovering the molecular mode ...... uone using a bacterial system.
@en
Uncovering the molecular mode ...... uone using a bacterial system.
@nl
type
label
Uncovering the molecular mode ...... uone using a bacterial system.
@ast
Uncovering the molecular mode ...... uone using a bacterial system.
@en
Uncovering the molecular mode ...... uone using a bacterial system.
@nl
prefLabel
Uncovering the molecular mode ...... uone using a bacterial system.
@ast
Uncovering the molecular mode ...... uone using a bacterial system.
@en
Uncovering the molecular mode ...... uone using a bacterial system.
@nl
P2093
P2860
P356
P1476
Uncovering the molecular mode ...... quone using a bacterial system
@en
P2093
Akhil B Vaidya
Elisabeth Darrouzet
Fevzi Daldal
Jason W Cooley
Maria Valkova-Valchanova
Michael T McIntosh
P2860
P304
27458-27465
P356
10.1074/JBC.M502319200
P407
P577
2005-05-24T00:00:00Z