Cortistatins A, B, C, and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex.
about
Targeting the Brain Reservoirs: Toward an HIV CureInvolucratusins A-H: Unusual Cadinane Dimers from Stahlianthus involucratus with Multidrug Resistance Reversal ActivityMarine pharmacology in 2005-2006: antitumour and cytotoxic compounds.Gold-catalyzed Intermolecular [4C + 3C] Cycloaddition Reactions.Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactivesSynthesis of cortistatins A, J, K and L.Synthesis of medicinally relevant terpenes: reducing the cost and time of drug discovery.An analog of the natural steroidal alkaloid cortistatin A potently suppresses Tat-dependent HIV transcription.Steroidal alkaloids from the marine sponge Corticium niger that inhibit growth of human colon carcinoma cells.Enantioselective synthesis of 2,2,5-tri- and 2,2,5,5-tetrasubstituted tetrahydrofurans via [4 + 2] cycloaddition and ring-opening cross-metathesisTotal synthesis of (±)-cortistatin J from furan.A hypervalent iodine-induced double annulation enables a concise synthesis of the pentacyclic core structure of the cortistatins.Asymmetric synthesis of dihydroindanes by convergent alkoxide-directed metallacycle-mediated bond formation.An Ounce of Tat Prevention Is Worth a Pound of Functional Cure.Synthetic studies toward (+)-cortistatin AConstructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.Towards a general diastereoselective route to oxabicyclo[3.2.1]octanes via a gold-catalysed cascade reactionThe Chemistry and Biology of Nakiterpiosin - C-nor-D-Homosteroids.Gold-catalyzed transannular [4+3] cycloaddition reactionsMarine-derived angiogenesis inhibitors for cancer therapy.A concise synthesis of the cortistatin core.A novel α,β-unsaturated nitrone-aryne [3+2] cycloaddition and its application in the synthesis of the cortistatin core.Marine pharmacology in 2005-6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervousChemoselectivity: the mother of invention in total synthesis.Anticancer steroids: linking natural and semi-synthetic compounds.Natural product synthesis in the age of scalability.Therapeutic Potential of Steroidal Alkaloids in Cancer and Other Diseases.Synthesis of the Cortistatin Pentacyclic Core by Alkoxide-Directed Metallacycle-Mediated Annulative Cross-Coupling.Didehydro-Cortistatin A: a new player in HIV-therapy?Terpenoid-Alkaloids: Their Biosynthetic Twist of Fate and Total SynthesisTrends in applying C-H oxidation to the total synthesis of natural products.Improving combination antiretroviral therapy by targeting HIV-1 gene transcription.Hydrogen-Atom Transfer Reactions.An Updated Review on Marine Anticancer Compounds: The Use of Virtual Screening for the Discovery of Small-Molecule Cancer Drugs.Four new polyoxygenated gorgosterols from the gorgonian Isis hippuris.Creation of readily accessible and orally active analogue of cortistatin a.Cortistatin A is a high-affinity ligand of protein kinases ROCK, CDK8, and CDK11.Stereodivergent synthesis of 17-alpha and 17-beta-alpharyl steroids: application and biological evaluation of D-ring cortistatin analogues.Synthesis and anti-angiogenic activity of cortistatin analogs.Synthesis of (+)-cortistatin A.
P2860
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P2860
Cortistatins A, B, C, and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@ast
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@en
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@nl
type
label
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@ast
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@en
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@nl
prefLabel
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@ast
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@en
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@nl
P2093
P921
P356
P1476
Cortistatins A, B, C, and D, a ...... rine sponge Corticium simplex.
@en
P2093
Andi Setiawan
Mami Sanagawa
Motomasa Kobayashi
Naoyuki Kotoku
Shunji Aoki
Yasuo Watanabe
P304
P356
10.1021/JA057404H
P407
P577
2006-03-01T00:00:00Z