Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133(+) glioma stem cells to temozolomide therapy.
about
Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic TargetsGlioma Stem Cells: Signaling, Microenvironment, and TherapyAberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and ChemoresistanceTwisted tango: brain tumor neurovascular interactionsCooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyUnderstanding glioma stem cells: rationale, clinical relevance and therapeutic strategiesBrain tumor stem cells: Molecular characteristics and their impact on therapyCD133, Selectively Targeting the Root of CancerElimination of Cancer Stem-Like Cells and Potentiation of Temozolomide Sensitivity by Honokiol in Glioblastoma Multiforme CellsAcute and fractionated irradiation differentially modulate glioma stem cell division kineticsCSNK1A1 and Gli2 as Novel Targets Identified Through an Integrative Analysis of Gene Expression Data, Protein-Protein Interaction and Pathways Networks in Glioblastoma Tumors: Can These Two Be Antagonistic Proteins?Gli1 contributes to cellular resistance to cisplatin through altered cellular accumulation of the drug.Promoting oligodendroglial-oriented differentiation of glioma stem cell: a repurposing of quetiapine for the treatment of malignant gliomaLarge-scale integrative network-based analysis identifies common pathways disrupted by copy number alterations across cancers.Notch signaling activation in pediatric low-grade astrocytomaTargeting the notch ligand JAGGED1 in both tumor cells and stroma in ovarian cancer.Immunobiology and signaling pathways of cancer stem cells: implication for cancer therapy.Hes1: a key role in stemness, metastasis and multidrug resistance.Glioma revisited: from neurogenesis and cancer stem cells to the epigenetic regulation of the nicheBone morphogenetic protein 7 sensitizes O6-methylguanine methyltransferase expressing-glioblastoma stem cells to clinically relevant dose of temozolomide.Complex oncogenic signaling networks regulate brain tumor-initiating cells and their progenies: pivotal roles of wild-type EGFR, EGFRvIII mutant and hedgehog cascades and novel multitargeted therapies.The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.Mechanisms of chemoresistance in cancer stem cells.The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence.NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200Combining hedgehog signaling inhibition with focal irradiation on reduction of pancreatic cancer metastasis.Prolonged inhibition of glioblastoma xenograft initiation and clonogenic growth following in vivo Notch blockadeIdentification of U251 glioma stem cells and their heterogeneous stem-like phenotypes.Targeting CD133 in an in vivo ovarian cancer model reduces ovarian cancer progression.EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.Targeting hyperactivated DNA-PKcs by KU0060648 inhibits glioma progression and enhances temozolomide therapy via suppression of AKT signaling.Characteristic features of stem cells in glioblastomas: from cellular biology to genetics.Tumor stem cells: A new approach for tumor therapy (Review).Glioblastoma stem cells: Molecular characteristics and therapeutic implicationsRecent advances in targeted therapy for glioblastoma.Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43.CD133 in brain tumor: the prognostic factor.Tumor-Initiating Cells: Emerging Biophysical Methods of Isolation.Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level.Lateral inhibition of Notch signaling in neoplastic cells.
P2860
Q26765758-EA8CA827-E3B6-460F-81B1-EB9F731A2D68Q26765854-B137B898-F03C-419A-9C03-8A71844F52BAQ26775006-EB5F870A-1F5C-4A70-9893-4749CBC949D3Q26849613-D84AA40D-6138-4E05-860F-04FC287FD678Q26865136-BC5AF43B-1F92-42AE-A41B-631F45A5E72DQ26995698-DF6E13F2-D878-4E24-8975-696AADDD8EA2Q27003138-6B6D6A16-ABF1-45FE-AA45-554DDB014CECQ28066353-10D7C3E7-256D-4C58-AF91-C8208E0491A4Q30048454-DB4848F8-B7CF-4ACF-8E9C-1C749BEF0874Q30537413-C783E10F-83FD-41BA-89C2-B610D54DFF82Q30867941-7890CD66-0CD7-4DEB-B94A-C74079337557Q33881681-1DCCD78F-1128-4A64-B109-BFB334B5207BQ33914005-FCF1EC1D-1E0A-4924-82A4-2E83FEE11EACQ34791962-9BBB3A1D-DB7A-42BD-9BF9-6A0FE8223972Q35170287-92293204-4372-476D-9625-89A45D7B9749Q35196364-04F394DE-66D2-432B-BD46-8F7D781EB924Q35984406-19C6641B-1094-4A57-A00A-0789EF50E8E6Q36213706-1E8E11A6-6111-4BB2-B292-905B3C753D6FQ36225175-1F3941A7-926E-4609-98CA-FF1D11EA104FQ36259173-186701A1-93B3-48B2-BF86-4FEC7A3EF47AQ36280796-5D9CC8CD-8A00-4698-B794-4C8CE39C16BFQ36288254-EB2FF035-8533-4C8B-A91F-345665FDD737Q36591484-D3E8F847-CF5F-4D2F-880C-B96205EA45BDQ36795940-CA0F01DA-FFAB-47AB-BC1F-F9CBF3772B09Q36866011-5BE46A95-76DC-46D8-B2AF-EC855D986BB9Q36926998-FE1D9036-36A1-403D-809B-AB22FB8C4E78Q36941324-F1982BDE-CD21-4D31-B29E-71381523895DQ37326086-A2E1D23B-38D5-40DF-9946-9BD88146A49EQ37532147-13818E5E-1D7B-4CAF-A036-5D7CC410AB31Q37660295-8487EA07-7CB3-4EAA-8C11-88275A319D52Q37688272-3F89B2FE-6C10-430C-991B-074C70E4CDA6Q37981219-2FB997B0-509F-4A34-81A9-E383D2F5269DQ38030535-D98C937D-3862-4EAC-A653-A98BEB8B1B72Q38207605-20B747A1-484E-49E7-8AC8-E6EEEB5D9CBFQ38539386-685E1386-496A-4B42-8BD8-3806F98F061FQ38593312-02349548-CAE6-464B-B003-30766A5D426CQ38722833-5260FBAD-EBDD-4F0A-AA65-CF5C5DA832DFQ38824383-37CE398C-8691-4CE6-9F52-C3F6944DB354Q38919180-906EF851-B32B-4B61-A9B2-CF4ACE260AC6Q38923462-B24A440D-FCDE-4396-BD18-BE4398BB1CD9
P2860
Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133(+) glioma stem cells to temozolomide therapy.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133
@nl
Inhibition of Sonic hedgehog a ...... cells to temozolomide therapy.
@ast
Inhibition of Sonic hedgehog a ...... cells to temozolomide therapy.
@en
type
label
Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133
@nl
Inhibition of Sonic hedgehog a ...... cells to temozolomide therapy.
@ast
Inhibition of Sonic hedgehog a ...... cells to temozolomide therapy.
@en
prefLabel
Inhibition of Sonic hedgehog and Notch pathways enhances sensitivity of CD133
@nl
Inhibition of Sonic hedgehog a ...... cells to temozolomide therapy.
@ast
Inhibition of Sonic hedgehog a ...... cells to temozolomide therapy.
@en
P2093
P2860
P1433
P1476
Inhibition of Sonic hedgehog a ...... cells to temozolomide therapy.
@en
P2093
Adam M Sonabend
Ilya V Ulasov
Maciej S Lesniak
Suvobroto Nandi
P2860
P2888
P304
P356
10.2119/MOLMED.2010.00062
P407
P577
2010-10-15T00:00:00Z
P5875
P6179
1068965271