High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts worse prognosis in patients. - Wikidata - awgldk - TriplyDB

High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts worse prognosis in patients.

High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts worse prognosis in patients.

http://www.wikidata.org/entity/Q34500720

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Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances Epigenetics meets radiation biology as a new approach in cancer treatment Role of epigenetic aberrations in the development and progression of human hepatocellular carcinoma Epigenetic regulation in hepatocellular carcinoma requires long noncoding RNAs Cytoplasmic expression of BAP1 as an independent prognostic biomarker for patients with gliomas The role of epigenetics in resistance to Cisplatin chemotherapy in lung cancer Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)Angiotensin II receptor blocker attenuates intrarenal renin-angiotensin-system and podocyte injury in rats with myocardial infarction.A "crossomics" study analysing variability of different components in peripheral blood of healthy caucasoid individuals.Decreased expression of Beclin 1 correlates closely with Bcl-xL expression and poor prognosis of ovarian carcinoma Protein expression of ZEB2 in renal cell carcinoma and its prognostic significance in patient survival The methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancers Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior H3K27me3 protein is a promising predictive biomarker of patients' survival and chemoradioresistance in human nasopharyngeal carcinoma High expression levels of unc-51-like kinase 1 as a predictor of poor prognosis in colorectal cancer.Histone modifications and cancer: biomarkers of prognosis?Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)TR4 Nuclear Receptor Alters the Prostate Cancer CD133+ Stem/Progenitor Cell Invasion via Modulating the EZH2-Related Metastasis Gene Expression Decreased expression of Sushi Domain Containing 2 correlates to progressive features in patients with hepatocellular carcinoma.Expression of programmed cell death-ligand 1 and its correlation with clinical outcomes in gliomas.Decreased expression of PTPN12 correlates with tumor recurrence and poor survival of patients with hepatocellular carcinoma.Epigenetics in hepatocellular carcinoma: an update and future therapy perspectives.Circulating Nucleosomes and Nucleosome Modifications as Biomarkers in Cancer Uncovering the roles of long non-coding RNAs in cancer stem cells.Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.New Tools for Molecular Therapy of Hepatocellular Carcinoma.Enhancing chemotherapy sensitivity by targeting PcG via the ATM/p53 pathway.Over-expression of protein tyrosine phosphatase 4A2 correlates with tumor progression and poor prognosis in nasopharyngeal carcinoma.Novel prognostic marker PRMT1 regulates cell growth via downregulation of CDKN1A in HCC.Bone marrow stromal cells enhance the survival of chronic lymphocytic leukemia cells by regulating HES-1 gene expression and H3K27me3 demethylation.

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High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts worse prognosis in patients.

http://www.wikidata.org/entity/Q34500720

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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Molecular Medicine

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Dan Xie

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Hui-Lan Rao

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Jing-Hui Hou

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Marie C Lin

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Mei Li

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Mu-Yan Cai

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Yi-Xin Zeng

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P2860

The language of covalent histone modifications

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

Control of developmental regulators by Polycomb in human embryonic stem cells

Epigenetics in cancer

Epigenetic stem cell signature in cancer

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma.

H3K27 trimethylation is an early epigenetic event of p16INK4a silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells

Novel advancements in the management of hepatocellular carcinoma in 2008.

The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.

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