Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2. - Wikidata - awgldk - TriplyDB

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

http://www.wikidata.org/entity/Q34501684

about

Does apical membrane GLUT2 have a role in intestinal glucose uptake?Sodium-glucose cotransporter 2 inhibition: cardioprotection by treating diabetes-a translational viewpoint explaining its potential salutary effects Update on the treatment of type 2 diabetes mellitus Efficacy, safety and regulatory status of SGLT2 inhibitors: focus on canagliflozin Mathematical modeling of renal tubular glucose absorption after glucose load Investigational anti-hyperglycemic agents: the future of type 2 diabetes therapy?The Concise Guide to PHARMACOLOGY 2013/14: transporters.Simulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family.The role of kidney in glucose homeostasis--SGLT2 inhibitors, a new approach in diabetes treatment.Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans Novel SGLT2 inhibitor: first-in-man studies of antisense compound is associated with unexpected renal effects.Human Peritoneal Mesothelial Cell Death Induced by High-Glucose Hypertonic Solution Involves Ca2+ and Na+ Ions and Oxidative Stress with the Participation of PKC/NOX2 and PI3K/Akt Pathways Forces and dynamics of glucose and inhibitor binding to sodium glucose co-transporter SGLT1 studied by single molecule force spectroscopy.Proximal tubule function and response to acidosis.Medication counselling with sodium glucose transporter 2 inhibitor therapy.Selective SGLT2 inhibition by tofogliflozin reduces renal glucose reabsorption under hyperglycemic but not under hypo- or euglycemic conditions in rats.SGLT2 inhibitors act from the extracellular surface of the cell membrane Sodium Glucose Co-Transporter-2 (SGLT2) Inhibitors: A Review of Their Basic and Clinical Pharmacology.The proximal tubule in the pathophysiology of the diabetic kidney.A novel delta current method for transport stoichiometry estimation.Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.Structural selectivity of human SGLT inhibitors.Sodium Glucose Cotransporter 2 (SGLT2) Plays as a Physiological Glucose Sensor and Regulates Cellular Contractility in Rat Mesangial Cells.Regulation of the human Na+-dependent glucose cotransporter hSGLT2.Clinical potential of sodium-glucose cotransporter 2 inhibitors in the management of type 2 diabetes The importance of being aromatic: π interactions in sodium symporters Stochastic steps in secondary active sugar transport.Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney.Functional identification and characterization of sodium binding sites in Na symporters.Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients.Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.Membrane transporters in a human genome-scale metabolic knowledgebase and their implications for disease.Real-time imaging of sodium glucose transporter (SGLT1) trafficking and activity in single cells Inhibition of SGLT2: a novel strategy for treatment of type 2 diabetes mellitus.SGLT2 inhibition in diabetes mellitus: rationale and clinical prospects.Empagliflozin for the treatment of Type 2 diabetes.Dapagliflozin: drug profile and its role in individualized treatment.Probing SGLT2 as a therapeutic target for diabetes: basic physiology and consequences.GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters.Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus.

P2860

Q27023552-2D460D79-C8C1-48FB-82F9-43B82AC0C8A5 Q28072765-7D1FA083-528F-40D1-8E83-2637076547C2 Q28073342-27BE6009-675D-4D8B-812A-EEAAB11B7385 Q28250844-2D71E4A0-2367-428C-9ACB-A866359B56B9 Q28539294-D83FBF49-1744-492B-B4C7-861EE9D022A3 Q30426407-A4812DEC-EE14-4FCD-83FD-C54A73973F0F Q30486743-FDAB28ED-5577-4E99-B525-755E2F0E6FFF Q30525263-4BDA848F-81F5-400E-96CA-97D7B950A065 Q30663494-BC2C0F09-BE61-4240-976D-50243F1B5736 Q33356608-0E3F69F8-4043-4045-BA58-7DE89D6B8328 Q33771405-DE3863CE-C016-48B1-8818-68DD95C42B0F Q33790023-46EB82BF-AB1B-48A0-9B8E-164A0DA42595 Q33985374-CF01FD85-4B2F-40EC-9915-CA1448C2CFBB Q34124765-D902AF9E-3E04-447F-9169-5595FB10D5B6 Q34228969-C6CDA1A1-CE5F-401F-B4D8-1E5532613608 Q34318349-A920F4B7-ECD9-4807-BB44-3D3F223CDC70 Q34400029-F0077168-FBD0-4B0E-832B-899AAF5A0F22 Q34726437-CE288DEF-9BB6-4611-A4FE-145617EDAF5D Q34979592-694416E1-7A07-4A88-8CF0-829BB85442D0 Q35537783-B8D57EEF-1700-4110-B928-5AEED581D429 Q35780729-97CD76FF-D623-441B-B50F-F3E58940CB93 Q35895528-4488363D-B52D-4027-BAB6-CACDFFF97111 Q35964702-49977877-D830-46EA-B0E3-8D1686B52F2A Q36175724-A61955B7-23D9-4682-8173-1EEADCA8A722 Q36221586-CC6A67F8-F704-4077-BF8F-FB352F7EC24D Q36470951-C66AAA36-879D-41A3-ACC1-D611A1741D12 Q37086472-FE05CBF2-2B95-42AB-ADBD-D9BBC09039B8 Q37253944-1B7DDAEF-0A7F-4B81-A84F-9088A9248B5F Q37340710-6C60D946-121C-4E59-BCB7-EDFB8004B110 Q37524302-93E41307-1EA2-45C6-8948-2E62E2BE6F90 Q37575461-FF681ED3-379F-4807-9E3B-9F4CC7AE3413 Q37629916-27408CDF-43BA-4C6D-BC90-8C75E46F5201 Q37642406-04892D98-873C-4179-BA86-D80F4DADEDC4 Q37846528-B4268AF0-4148-4DD5-88FB-9C96226A364B Q37981884-3DB04C08-81BF-45E3-AF31-5D5958225315 Q38203327-C23137F1-731C-4E95-A3A9-70A687F860DB Q38308333-62437E9B-723D-4029-9EEB-D6CF3D9C175D Q38330456-083DEAA5-029F-4BE0-BBFB-90F490849952 Q38663958-FBF35E0F-EA34-4DF9-B3A1-E441B316B284 Q38783130-676368A6-A0D9-43D4-828D-ACFA97F280F5

P2860

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

http://www.wikidata.org/entity/Q34501684

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@ast

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@en

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@nl

type

label

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@ast

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@en

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@nl

prefLabel

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@ast

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@en

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@nl

P1433

Q34501684-CCB66DD0-4E04-4A5C-9B52-5A3216633632

P1476

Q34501684-C7992771-A151-4599-9BD1-90895E8650D9

P2093

Q34501684-0275948A-7CC0-44B5-8447-633F0F6CA154

Q34501684-1CDB8D44-90F8-4833-BC4C-E9D2AFBFC5F6

Q34501684-3AC24AE2-EC94-4D19-94B9-3802B48E2BD6

Q34501684-4A507F99-07CE-4448-824E-D4EF96B90E87

Q34501684-4DDC7B4D-E579-4332-AA2B-B1C9FC6F95A7

Q34501684-67A4209F-5C6D-4321-B624-1C24C0AC65AE

P2860

Q34501684-2AA9DFA7-C8CA-45D5-9875-C8DE14883DEE

Q34501684-2D7AD451-6A56-4FBF-A8AB-AE22F70649FB

Q34501684-353CD485-4B55-40E3-89A2-7A8E480A76FB

Q34501684-38A70A23-5A7F-48B6-9ED8-E398F037B52A

Q34501684-41DA0F33-2D9A-46F1-A979-9EE56278A6DA

Q34501684-456DE102-37E5-4ABF-90D9-22D3D2D2D873

Q34501684-46AE3851-B66F-4DBA-A1CB-9661EC13A484

Q34501684-4817AD88-1151-4380-B8D9-8FD6B1142ADF

Q34501684-4D790DC0-ACB6-4568-A82F-2593F1FD7C7F

Q34501684-5741BBB3-7CB1-40AE-894D-6DB2A2B9F86A

P304

Q34501684-965F7398-4BEB-4DBC-82F5-5DF3DCA02AB9

P31

Q34501684-893C74FE-6F33-4A6B-99E3-1BC37F01DF96

P356

Q34501684-0E095F52-85D9-43F3-8DEE-B8BC45E4A3D9

P433

Q34501684-49B6944A-762C-486D-B681-CAB7C09F06EF

P478

Q34501684-7A8FD42E-296F-4FCE-9B16-2B2BDF73D185

P577

Q34501684-7A3B7840-5F8B-4CC3-AD98-3CBDA8E49A65

P698

Q34501684-45D96893-F078-43F9-83B5-9E0F106ECDA8

P921

Q34501684-22054C7D-0B59-477D-9E09-C1C2D14509DB

Q34501684-625C9501-2573-4EA3-B5D8-F25235FE7409

Q34501684-DD0DDB05-FD3E-466B-9945-E38BDB0212B9

Q34501684-b33d9762-a107-4014-acf6-7690f46e667b

P932

Q34501684-DEE2A3DB-B98B-4A44-A874-D78AC1849D10

P356

AJPCELL.00388.2010

P1433

American Journal of Physiology - Cell Physiology

P1476

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

@en

P2093

Andrew A Voss

http://www.w3.org/2001/XMLSchema#string

Bruce A Hirayama

http://www.w3.org/2001/XMLSchema#string

Charles S Hummel

http://www.w3.org/2001/XMLSchema#string

Chuan Lu

http://www.w3.org/2001/XMLSchema#string

Donald D F Loo

http://www.w3.org/2001/XMLSchema#string

Ernest M Wright

http://www.w3.org/2001/XMLSchema#string

P2860

Thermodynamic determination of the Na+: glucose coupling ratio for the human SGLT1 cotransporter.

The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport

Renal Na(+)-glucose cotransporters

Cloning of a human kidney cDNA with similarity to the sodium-glucose cotransporter

Molecular analysis of the SGLT2 gene in patients with renal glucosuria

Expression cloning and cDNA sequencing of the Na+/glucose co-transporter

Common mechanisms of inhibition for the Na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransporters

Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney

The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

Dapagliflozin monotherapy in type 2 diabetic patients with inadequate glycemic control by diet and exercise: a randomized, double-blind, placebo-controlled, phase 3 trial.

P304

C14-21

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1152/AJPCELL.00388.2010

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

300

http://www.w3.org/2001/XMLSchema#string

P577

2010-10-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20980548

http://www.w3.org/2001/XMLSchema#string

P921

sodium ion import across plasma membrane

Solute carrier family 5 member 2

Solute carrier family 5 member 1

P932

3023189

http://www.w3.org/2001/XMLSchema#string