Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity. - Wikidata - awgldk - TriplyDB

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

http://www.wikidata.org/entity/Q34507318

about

Modelling amyotrophic lateral sclerosis: progress and possibilities Memory deficits, gait ataxia and neuronal loss in the hippocampus and cerebellum in mice that are heterozygous for Pur-alpha.Altered mRNP granule dynamics in FTLD pathogenesis.Stress granules at the intersection of autophagy and ALS.Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS.Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand.Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.PURA, the gene encoding Pur-alpha, member of an ancient nucleic acid-binding protein family with mammalian neurological functions.The roles of intrinsic disorder-based liquid-liquid phase transitions in the "Dr. Jekyll-Mr. Hyde" behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD.High content screen for identifying small-molecule LC3B-localization modulators in a renal cancer cell line.

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P2860

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

http://www.wikidata.org/entity/Q34507318

description

2016 nî lūn-bûn

@nan

2016 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

name

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@ast

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@en

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@nl

type

label

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@ast

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@en

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@nl

prefLabel

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@ast

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@en

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.

@nl

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S00401-015-1530-0

P1433

Acta Neuropathologica

P1476

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity

@en

P2093

Dianne C Daniel

http://www.w3.org/2001/XMLSchema#string

Earl W Godfrey

http://www.w3.org/2001/XMLSchema#string

Edward M Johnson

http://www.w3.org/2001/XMLSchema#string

Frank Shewmaker

http://www.w3.org/2001/XMLSchema#string

Ian Casci

http://www.w3.org/2001/XMLSchema#string

J Gavin Daigle

http://www.w3.org/2001/XMLSchema#string

John Monaghan

http://www.w3.org/2001/XMLSchema#string

Kevin McAvoy

http://www.w3.org/2001/XMLSchema#string

Nandini Ramesh

http://www.w3.org/2001/XMLSchema#string

Piera Pasinelli

http://www.w3.org/2001/XMLSchema#string

P2860

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment

The HeLa Pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replication

Association of human Pur alpha with the retinoblastoma protein, Rb, regulates binding to the single-stranded DNA Pur alpha recognition element

Stress granule assembly is mediated by prion-like aggregation of TIA-1

Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein

Altered ribostasis: RNA-protein granules in degenerative disorders

Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

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s00401-015-1530-0

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605-620

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scholarly article

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10.1007/S00401-015-1530-0

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4

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131

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Karthik Krishnamurthy

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2016-01-04T00:00:00Z

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289244950

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26728149

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4791193

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