Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning - Wikidata - awgldk - TriplyDB

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

http://www.wikidata.org/entity/Q34511046

about

Integrated physiology and systems biology of PPARα Mechanisms of intrahepatic triglyceride accumulation Mechanisms of gene regulation by fatty acids Comparative gene identification-58/α/β hydrolase domain 5: more than just an adipose triglyceride lipase activator?Hepatic lipid droplet biology: Getting to the root of fatty liver Biology and pathobiology of lipid droplets and their potential role in the protection of the organ of Corti.Testosterone replacement ameliorates nonalcoholic fatty liver disease in castrated male rats ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism.Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet.Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet.Fenofibrate, a peroxisome proliferator-activated receptor α agonist, alters triglyceride metabolism in enterocytes of mice.From whole body to cellular models of hepatic triglyceride metabolism: man has got to know his limitations The g0/g1 switch gene 2 is an important regulator of hepatic triglyceride metabolism.ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1α/PPAR-α signaling Fatty acid signaling: the new function of intracellular lipases.Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance.Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells.Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.Isothiocyanate-rich Moringa oleifera extract reduces weight gain, insulin resistance, and hepatic gluconeogenesis in mice.The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction Skeletal muscle lipid flux: running water carries no poison FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.Perilipins: lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection Perilipin 5, a lipid droplet protein adapted to mitochondrial energy utilization.Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.Studying lipolysis in adipocytes by combining siRNA knockdown and adenovirus-mediated overexpression approaches.Mice lacking δ-opioid receptors resist the development of diet-induced obesity Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply.Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis.Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation.Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress.The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis.Distinct roles for alpha-beta hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling.Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation.Increased lipolysis and altered lipid homeostasis protect γ-synuclein-null mutant mice from diet-induced obesity.Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling

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P2860

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

http://www.wikidata.org/entity/Q34511046

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2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Andrew S Greenberg

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Douglas G Mashek

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Mara T Mashek

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P2860

Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells

Mechanism of action of fibrates on lipid and lipoprotein metabolism

PPARalpha deficiency reduces insulin resistance and atherosclerosis in apoE-null mice

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure

OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization

Mitochondrial glycerol-3-phosphate acyltransferase-1 directs the metabolic fate of exogenous fatty acids in hepatocytes

Arylacetamide deacetylase attenuates fatty-acid-induced triacylglycerol accumulation in rat hepatoma cells

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20967758

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