Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the carney complex.
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Pituitary pathology in Carney complex patientsMolecular genetics of adrenocortical tumor formation and potential pharmacologic targetsCarney complex: an updateImproved discrimination of melanotic schwannoma from melanocytic lesions by combined morphological and GNAQ mutational analysis.Alterations of Phosphodiesterases in Adrenocortical TumorsMEN1, MEN4, and Carney Complex: Pathology and Molecular GeneticsHuman tumors associated with Carney complex and germline PRKAR1A mutations: a protein kinase A disease!A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasiaPancreatic ductal and acinar cell neoplasms in Carney complex: a possible new associationGrowth hormone-secreting tumors: genetic aspects and data from animal modelsHaploinsufficiency at the protein kinase A RI alpha gene locus leads to fertility defects in male mice and menMolecular mechanisms promoting the pathogenesis of Schwann cell neoplasmsProtein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors.Recurrent right ventricular cardiac myxoma in a patient with Carney complex: a case report.[Absence of PRKAR1A loss of heterozygosity in laser-captured microdissected pigmented nodular adrenocortical tissue from a patient with Carney complex caused by the novel nonsense mutation p.Y21X].Association of the M1V PRKAR1A mutation with primary pigmented nodular adrenocortical disease in two large families.Interaction of the regulatory subunit of the cAMP-dependent protein kinase with PATZ1 (ZNF278).PRKAR1A gene analysis and protein kinase A activity in endometrial tumors.Familial micronodular adrenocortical disease, Cushing syndrome, and mutations of the gene encoding phosphodiesterase 11A4 (PDE11A).p90 ribosomal S6 kinase 1 (RSK1) and the catalytic subunit of protein kinase A (PKA) compete for binding the pseudosubstrate region of PKAR1alpha: role in the regulation of PKA and RSK1 activities.Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signalingThyroid cancer: current molecular perspectives.Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumorsCell-type specific expression of a dominant negative PKA mutation in mice.Regulation of steroidogenesis in a primary pigmented nodular adrenocortical disease-associated adenoma leading to virilization and subclinical Cushing's syndrome.Alternate protein kinase A activity identifies a unique population of stromal cells in adult bonePRKAR1A and the evolution of pituitary tumors.Mutations and polymorphisms in the gene encoding regulatory subunit type 1-alpha of protein kinase A (PRKAR1A): an update.Mouse models of endocrine tumours.Solid tumors associated with multiple endocrine neoplasias.Ectopic thymus presenting as a thyroid nodule in a patient with the Carney complexClinical genetics of multiple endocrine neoplasias, Carney complex and related syndromes.Carney complex and other conditions associated with micronodular adrenal hyperplasias.Carney complex (CNC).Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype.How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?Rare and unusual endocrine cancer syndromes with mutated genes.Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.A novel PRKAR1A mutation associated with hepatocellular carcinoma in a young patient and a variable Carney complex phenotype in affected subjects in older generations.
P2860
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P2860
Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the carney complex.
description
2000 nî lūn-bûn
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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Genetic heterogeneity and spec ...... ients with the carney complex.
@ast
Genetic heterogeneity and spec ...... ients with the carney complex.
@en
Genetic heterogeneity and spec ...... ients with the carney complex.
@nl
type
label
Genetic heterogeneity and spec ...... ients with the carney complex.
@ast
Genetic heterogeneity and spec ...... ients with the carney complex.
@en
Genetic heterogeneity and spec ...... ients with the carney complex.
@nl
prefLabel
Genetic heterogeneity and spec ...... ients with the carney complex.
@ast
Genetic heterogeneity and spec ...... ients with the carney complex.
@en
Genetic heterogeneity and spec ...... ients with the carney complex.
@nl
P2093
P356
P1476
Genetic heterogeneity and spec ...... ients with the carney complex.
@en
P2093
P304
P356
10.1093/HMG/9.20.3037
P577
2000-12-01T00:00:00Z