Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen - Wikidata - awgldk - TriplyDB

Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen

Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen

http://www.wikidata.org/entity/Q34515039

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Approaches to vaccines against Orientia tsutsugamushi Single dose novel Salmonella vaccine enhances resistance against visceralizing L. major and L. donovani infection in susceptible BALB/c mice Role of T3SS-1 SipD Protein in Protecting Mice against Non-typhoidal Salmonella Typhimurium IMMUNOCAT-a data management system for epitope mapping studies Identification of a common immune signature in murine and human systemic Salmonellosis.A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.DFI-seq identification of environment-specific gene expression in uropathogenic Escherichia coli.Interferon-γ and proliferation responses to Salmonella enterica Serotype Typhi proteins in patients with S. Typhi Bacteremia in Dhaka, Bangladesh.Vaccine development in Staphylococcus aureus: taking the biofilm phenotype into consideration.Polyfunctional CD4+ T cell responses to immunodominant epitopes correlate with disease activity of virulent Salmonella Immunity to intracellular Salmonella depends on surface-associated antigens.Salmonella enterica highly expressed genes are disease specific.Immunogenic and invasive properties of Brucella melitensis 16M outer membrane protein vaccine candidates identified via a reverse vaccinology approach Parallel exploitation of diverse host nutrients enhances Salmonella virulence.Polymicrobial interactions: impact on pathogenesis and human disease.RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium Tracking the dynamics of T-cell activation in response to Salmonella infection.Unraveling the secret lives of bacteria: use of in vivo expression technology and differential fluorescence induction promoter traps as tools for exploring niche-specific gene expression An oral recombinant Salmonella enterica serovar Typhimurium mutant elicits systemic antigen-specific CD8+ T cell cytokine responses in mice Tracking the dynamics of salmonella specific T cell responses.T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria.Typhoid fever & vaccine development: a partially answered question.Host-Brucella interactions and the Brucella genome as tools for subunit antigen discovery and immunization against brucellosis.Identification of Protective Antigens for Vaccination against Systemic Salmonellosis.Dual Immunization with SseB/Flagellin Provides Enhanced Protection against Salmonella Infection Mediated by Circulating Memory Cells.Vaccination with a single CD4 T cell peptide epitope from a Salmonella type III-secreted effector protein provides protection against lethal infection.Enhanced immunogenicity in the murine airway mucosa with an attenuated Salmonella live vaccine expressing OprF-OprI from Pseudomonas aeruginosa.Intranasal Vaccination With Salmonella-Derived Serodominant Secreted Effector Protein B Associated With Gas-Filled Microbubbles Partially Protects Against Gut Infection in Mice.Systematic analysis of the SsrAB virulon of Salmonella enterica.Optimal place of a foreign gene in the genome of viral haemorrhagic septicaemia virus (VHSV) for development of VHSV-based viral-vectored vaccines.Mtb32 is a promising tuberculosis antigen for DNA vaccination in pre- and post-exposure mouse models.Characterization and protective efficacy of type three secretion proteins as a broadly protective subunit vaccine against Salmonella enterica serovars.Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection.The hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages.A cell-based infection assay identifies efflux pump modulators that reduce bacterial intracellular load.

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Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen

http://www.wikidata.org/entity/Q34515039

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2004 nî lūn-bûn

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Antigen selection based on exp ...... for an intracellular pathogen

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Antigen selection based on exp ...... for an intracellular pathogen

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Claudia Rollenhagen

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Dirk Bumann

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Konstantin Rizos

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Meike Sörensen

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Robert Hurvitz

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P2860

Complete genome sequence of Salmonella enterica serovar Typhimurium LT2

Global analysis of protein expression in yeast

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

FACS-optimized mutants of the green fluorescent protein (GFP)

Examination of Salmonella gene expression in an infected mammalian host using the green fluorescent protein and two-colour flow cytometry.

Salmonella typhimurium thyA mutants fail to grow intracellularly in vitro and are attenuated in mice.

Cell-specific proteins synthesized by Salmonella typhimurium.

Novel approaches to monitor bacterial gene expression in infected tissue and host.

Epitope tagging of chromosomal genes in Salmonella.

Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells.

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