Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease. - Wikidata - awgldk - TriplyDB

Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.

Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.

http://www.wikidata.org/entity/Q34515645

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Striatal Plasticity in L-DOPA- and Graft-Induced Dyskinesia; The Common Link?Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells.Intrastriatal Grafting of Chromospheres: Survival and Functional Effects in the 6-OHDA Rat Model of Parkinson's Disease The germline/soma dichotomy: implications for aging and degenerative disease Chemical Control of Grafted Human PSC-Derived Neurons in a Mouse Model of Parkinson's Disease Efficient generation of hPSC-derived midbrain dopaminergic neurons in a fully defined, scalable, 3D biomaterial platform.Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents.Moving stem cells to the clinic: potential and limitations for brain repair Pluripotent stem cells: the last 10 years.Sorting the wheat from the chaff in dopamine neuron-based cell therapies.Optimization of the magnetic labeling of human neural stem cells and MRI visualization in the hemiparkinsonian rat brain Advances in reprogramming-based study of neurologic disorders Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease.Cell-based therapies for Parkinson disease—past insights and future potential.Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?Development of stem cell-based therapy for Parkinson's disease.Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor.Excessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors.Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor Semaphorin 3C Released from a Biocompatible Hydrogel Guides and Promotes Axonal Growth of Rodent and Human Dopaminergic Neurons hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation.The transcriptomes of novel marmoset monkey embryonic stem cell lines reflect distinct genomic features.Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1.Scale Invariant Disordered Nanotopography Promotes Hippocampal Neuron Development and Maturation with Involvement of Mechanotransductive Pathways.The effect of magnetic nanoparticles on neuronal differentiation of induced pluripotent stem cell-derived neural precursors.Effects of Feeder Cells on Dopaminergic Differentiation of Human Embryonic Stem Cells.An Integrated Miniature Bioprocessing for Personalized Human Induced Pluripotent Stem Cell Expansion and Differentiation into Neural Stem Cells Induced dopaminergic neurons: A new promise for Parkinson's disease.Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking.In Vivo Assessment of Stem Cells for Treating Neurodegenerative Disease: Current Approaches and Future Prospects Neural Stem Cells Derived From Human Parthenogenetic Stem Cells Engraft and Promote Recovery in a Nonhuman Primate Model of Parkinsons Disease.Clinical translation of stem cell transplantation in Parkinson's disease.Current Neurogenic and Neuroprotective Strategies to Prevent and Treat Neurodegenerative and Neuropsychiatric Disorders.Current status of pluripotent stem cells: moving the first therapies to the clinic.Treatment of Parkinson's disease using cell transplantation.

P2860

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P2860

Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.

http://www.wikidata.org/entity/Q34515645

description

2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Human ESC-derived dopamine neu ...... model of Parkinson's disease.

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Human ESC-derived dopamine neu ...... model of Parkinson's disease.

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Human ESC-derived dopamine neu ...... model of Parkinson's disease.

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Human ESC-derived dopamine neu ...... model of Parkinson's disease.

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Human ESC-derived dopamine neu ...... model of Parkinson's disease.

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Human ESC-derived dopamine neu ...... model of Parkinson's disease.

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Human ESC-derived dopamine neu ...... model of Parkinson's disease.

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J.STEM.2014.09.017

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P1476

Human ESC-derived dopamine neu ...... model of Parkinson's disease.

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P2093

Bengt Mattsson

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Elsa Diguet

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Philippe Hantraye

http://www.w3.org/2001/XMLSchema#string

Yann Bramoulle

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P2860

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection

The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease.

The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons.

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.

Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease.

Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease.

Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports.

Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation.

Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease.

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653-665

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10.1016/J.STEM.2014.09.017

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5

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15

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Anselme Perrier

Anders Björklund

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2014-11-06T00:00:00Z

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267924680

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25517469

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P921

Parkinson's disease

P932

4232736

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