An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers.

An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers.

Item
http://www.wikidata.org/entity/Q34517465
A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH2 versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2: A Bivalent Advantage.A Macrocyclic Agouti-Related Protein/[Nle4,DPhe7]α-Melanocyte Stimulating Hormone Chimeric Scaffold Produces Subnanomolar Melanocortin Receptor Ligands.Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016.Ac-Trp-DPhe(p-I)-Arg-Trp-NH2, a 250-Fold Selective Melanocortin-4 Receptor (MC4R) Antagonist over the Melanocortin-3 Receptor (MC3R), Affects Energy Homeostasis in Male and Female Mice Differently.Comparative in Vivo Investigation of Intrathecal and Intracerebroventricular Administration with Melanocortin Ligands MTII and AGRP into Mice.1,2,3-Triazole Rings as a Disulfide Bond Mimetic in Chimeric AGRP-Melanocortin Peptides: Design, Synthesis, and Functional Characterization.Structure-Activity Relationship Studies on a Macrocyclic Agouti-Related Protein (AGRP) Scaffold Reveal Agouti Signaling Protein (ASP) Residue Substitutions Maintain Melanocortin-4 Receptor Antagonist Potency and Result in Inverse Agonist Pharmacolog
P2860

An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers.

Item
http://www.wikidata.org/entity/Q34517465
description
2016 nî lūn-bûn
@nan
2016 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մարտին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@ast
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@en
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@nl
type
label
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@ast
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@en
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@nl
prefLabel
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@ast
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@en
An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@nl
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An in Vitro and in Vivo Invest ...... anocortin Receptor Homodimers.
@en
P2093
P2860
P304
P31
P356
10.1021/ACS.JMEDCHEM.5B01894
P407
P433
P478
P577
P698
P932