Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA. - Wikidata - awgldk - TriplyDB

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.

http://www.wikidata.org/entity/Q34519307

about

The effects of hypoxia on the stemness properties of human dental pulp stem cells (DPSCs).Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment.A unified model of the hierarchical and stochastic theories of gastric cancer.Transcriptome-wide N 6 -methyladenosine methylome profiling of porcine muscle and adipose tissues reveals a potential mechanism for transcriptional regulation and differential methylation pattern Cancer stem cell heterogeneity: origin and new perspectives on CSC targeting m6A-Driver: Identifying Context-Specific mRNA m6A Methylation-Driven Gene Interaction Networks.Post-transcriptional gene regulation by mRNA modifications.Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.Targetable T-type Calcium Channels Drive Glioblastoma.Hypoxia-Mediated Epigenetic Regulation of Stemness in Brain Tumor Cells.m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program.Influence of Cholesterol on the Oxygen Permeability of Membranes: Insight from Atomistic Simulations.Breast cancer stem cell: the roles and therapeutic implications.Beyond the Triplet Code: Context Cues Transform Translation.Hypoxia-inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype.The Epitranscriptome of Noncoding RNAs in Cancer.Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function.The RNA Modification N6-methyladenosine and Its Implications in Human Disease.Dynamic RNA Modifications in Gene Expression Regulation.Maintenance of redox homeostasis by hypoxia-inducible factors.Breast cancer stem cells as last soldiers eluding therapeutic burn: A hard nut to crack.Hypoxia: Signaling the Metastatic Cascade.METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N6 -methyladenosine-dependent primary MicroRNA processing.Emerging links between m6A and misregulated mRNA methylation in cancer N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.NANOG reprograms prostate cancer cells to castration resistance via dynamically repressing and engaging the AR/FOXA1 signaling axis.Epitranscriptomic influences on development and disease.Engineered Breast Cancer Cell Spheroids Reproduce Biologic Properties of Solid Tumors.ZNF217/ZFP217 Meets Chromatin and RNA.The Dark Side of the Epitranscriptome: Chemical Modifications in Long Non-Coding RNAs.Hypoxic Stress-Induced Tumor and Immune Plasticity, Suppression, and Impact on Tumor Heterogeneity.Reduced m6A mRNA methylation is correlated with the progression of human cervical cancer.Pulmonary function impairment predicted poor prognosis of patients with hepatocellular carcinoma after hepatectomy.m6AVar: a database of functional variants involved in m6A modification.ALKBH10B Is an RNA N6-Methyladenosine Demethylase Affecting Arabidopsis Floral Transition.Role of N6-methyladenosine modification in cancer.m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells.Radiotherapy and Glioma Stem Cells: Searching for Chinks in Cellular Armor.The DEAD-Box RNA Helicase DDX3 Interacts with m6A RNA Demethylase ALKBH5.Rethinking m6A Readers, Writers, and Erasers.

P2860

Q30822628-57AFC1C2-6C43-4ACA-A4F1-ACC1E19723B7 Q33572252-4A4702C7-84AA-4C81-A109-6040E5970006 Q33577624-75740A26-33CB-472E-9C0C-6C0020A59A2D Q33617811-4BB5CDCF-85A0-4DF6-8375-F73E06950EBD Q33649230-D45A2BF4-4226-40D0-A322-FA74FCDBD66E Q36233884-189FF2C6-BA34-431F-B499-D3821C5A78BD Q37515917-14913AA6-FB1B-43B2-9C7E-1C4AA251C2D5 Q37662078-35A1EE61-CF81-44DC-BB5F-484194ACD37E Q38438756-AC16E05A-A605-4547-9CA9-EE1D8C4F5C91 Q38708928-7348D500-5ADB-4B69-A73B-259B385C2C18 Q38710467-818DD3B7-9454-46A7-BAAF-84A5969BD1A5 Q38738003-CB38DFE7-8CB6-4091-8E3B-AF2ED0273A91 Q38929036-7E12F75E-1520-408C-B715-07C9C7FC3A07 Q39041499-6A91D7D9-2677-4250-8CBF-C046989D5F8B Q39051074-C6325186-B8A1-4EC8-BA7C-3387DCB58D8D Q39188703-DEBBC320-6036-40CB-BE5C-3CDA44EEEC9E Q39277299-972B0B89-B38F-461A-BC1E-B53770E03BCF Q39323232-A38036DC-DFC1-4996-8391-DE81BE107679 Q39378718-D6E6C9CB-B384-400F-A1B6-1D74A7AD0140 Q39380299-A70FC448-B9A3-47C8-8D4B-DB80193B2ADE Q39443694-48CBE94D-7960-41BE-A096-E86DE7F330A2 Q39456897-EBC9B957-F48D-484D-8073-30FFAF621E07 Q40520642-0A988C4D-E692-4979-88FC-DCF60286F15B Q41380298-EB0F6E92-9E84-490F-B99E-65635B6AC2B2 Q41432736-18F37411-8C13-4FFE-BE69-72D37C43927C Q42368758-EF8491FF-A953-488E-B835-976F7259BDF1 Q42643390-59F7C4E1-1BCE-4840-8CE9-666DE8D17EB8 Q42835560-342A8E4A-43EA-46A2-BAA9-46338B63E3E2 Q45245581-44880424-843F-4F29-89D6-E4677ACA1BCA Q47101298-EC632157-627E-44DF-8934-DFF667967A8E Q47120916-A8066808-8F40-4012-AD01-0B56313F8690 Q47131519-4DED53DE-74DC-4B24-9102-E2F2A394AEAF Q47139999-223F8F53-A98E-425E-BAEE-7E6B49F5A80A Q47159279-A087BEFE-FE31-4F58-A861-376F1202EA21 Q47309407-CA58CBAB-7399-46E2-B692-CA995521A100 Q47567064-0F4553E8-EB67-420B-8685-A55A811DC1EA Q47583443-5F5FD0B6-63EE-4029-8CEC-6F72AA57C2CB Q47849042-68ADF77D-3FC7-4259-9E51-56B6458E0534 Q47864860-3F64F3DF-BCC3-41B0-8830-D272A0AC70A6 Q48009024-84FC5E2F-FF71-4D9D-9010-BEEB736636E7

P2860

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.

http://www.wikidata.org/entity/Q34519307

description

2016 nî lūn-bûn

@nan

2016 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի մարտին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

name

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@ast

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@en

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@nl

type

label

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@ast

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@en

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@nl

prefLabel

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@ast

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@en

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@nl

P1433

Q34519307-CB02FFED-09AF-42F7-8A67-2178A6C93675

P1476

Q34519307-D7697B2E-4F91-4CA5-B651-2DD3BBEB53D4

P2093

Q34519307-331E632A-EEBF-408B-ADF5-D690FA493F0E

Q34519307-3788AB68-2B65-4572-9D8F-FAEACF98CE7B

Q34519307-54C7BA19-FCD7-4751-B8BB-B84ADEE4A52C

Q34519307-7273B30E-2127-4845-AD7E-3365ACBF8724

Q34519307-8FC48C21-125E-4565-8E41-3D6DE83DFBFC

Q34519307-A4842353-97C0-4F03-B5F2-B7BB3FEC0156

Q34519307-F00261FD-FD62-40B1-89AA-A6F043B34FA3

P2860

Q34519307-07856D35-A99F-4620-AF13-B09E6B487C1B

Q34519307-07B59254-DB3B-40FE-ACF2-D124F53EA916

Q34519307-081D3C11-E06A-4B1F-BC57-215E914D46EE

Q34519307-0B5BF892-EC81-4CB0-8CF1-E1F55791B5D8

Q34519307-0C1EA24B-EBD8-444D-83B4-A27A82856192

Q34519307-16CF6762-760C-40AB-8608-0B12CC941B48

Q34519307-29EF4DB8-2ED7-40F6-B026-70AE72404D4D

Q34519307-2D93C4AB-34E0-4EDB-8CC8-A74474908DF8

Q34519307-3F597B73-A7D4-4543-9F67-FAE5828FE885

Q34519307-42AE7EAB-EFB7-4D1A-B019-E2D241BE16DA

P304

Q34519307-0C109298-463B-49B2-AB91-5EEBD34F7EFF

P31

Q34519307-30E80892-8F95-4DAD-9B7B-159D88B58D75

P356

Q34519307-5FB4EC50-4A4C-4F17-B32B-031B8FF9E303

P407

Q34519307-C2880EC7-CF3B-4123-BB51-45AFC234A3CF

P433

Q34519307-E45AC09C-1087-470C-8358-F277BC860B40

P478

Q34519307-A8F4C01F-0D05-4E33-8F0B-710727A3CFC9

P50

Q34519307-2BCCDA2F-2AE6-44B8-90F2-C40118E4A8A3

P577

Q34519307-D102F247-7033-4948-ADD7-A0CF93313594

P698

Q34519307-9B1A96A1-02A7-4020-936A-B4A296A84077

P921

Q34519307-F0EBEABC-6CFC-40CA-9B6A-3464938504D5

P932

Q34519307-930A80AB-D2A1-43D2-A51D-C448306ADC94

P356

PNAS.1602883113

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Hypoxia induces the breast can ...... A-demethylation of NANOG mRNA.

@en

P2093

Chuanzhao Zhang

http://www.w3.org/2001/XMLSchema#string

Debangshu Samanta

http://www.w3.org/2001/XMLSchema#string

Haiquan Lu

http://www.w3.org/2001/XMLSchema#string

Huimin Zhang

http://www.w3.org/2001/XMLSchema#string

Ivan Chen

http://www.w3.org/2001/XMLSchema#string

John W Bullen

http://www.w3.org/2001/XMLSchema#string

Xiaoshun He

http://www.w3.org/2001/XMLSchema#string

P2860

ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility

N6-methyladenosine-dependent regulation of messenger RNA stability

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

Core transcriptional regulatory circuitry in human embryonic stem cells

N6-methyladenosine marks primary microRNAs for processing

Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

Prospective identification of tumorigenic breast cancer cells

Hypoxia-inducible factors in physiology and medicine

P304

E2047-56

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1602883113

http://www.w3.org/2001/XMLSchema#string

P407

P433

14

http://www.w3.org/2001/XMLSchema#string

P478

113

http://www.w3.org/2001/XMLSchema#string

P50

Gregg L. Semenza

P577

2016-03-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27001847

http://www.w3.org/2001/XMLSchema#string

P921

P932

4833258

http://www.w3.org/2001/XMLSchema#string