Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity - Wikidata - awgldk - TriplyDB

Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity

Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity

http://www.wikidata.org/entity/Q34519502

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Selenium and diabetes--evidence from animal studies Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models?Redox homeostasis in pancreatic β cells Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications Prolonged dietary selenium deficiency or excess does not globally affect selenoprotein gene expression and/or protein production in various tissues of pigs Secondary analysis of publicly available data reveals superoxide and oxygen radical pathways are enriched for associations between type 2 diabetes and low-frequency variants.Superoxide dismutase 1 loss disturbs intracellular redox signaling, resulting in global age-related pathological changes.Mouse Models of Oxidative Stress Indicate a Role for Modulating Healthy Aging.Two tales of antioxidant enzymes on β cells and diabetes.Reduced utilization of selenium by naked mole rats due to a specific defect in GPx1 expression.Knockout of SOD1 promotes conversion of selenocysteine to dehydroalanine in murine hepatic GPX1 protein.Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair.Nutrient-dependent requirement for SOD1 in lifespan extension by protein restriction in Drosophila melanogaster.Mitochondrial hormesis in pancreatic β cells: does uncoupling protein 2 play a role?Knockout of SOD1 alters murine hepatic glycolysis, gluconeogenesis, and lipogenesis Dietary selenium deficiency partially rescues type 2 diabetes-like phenotypes of glutathione peroxidase-1-overexpressing male mice.A high-selenium diet induces insulin resistance in gestating rats and their offspring Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic β Cell Dysfunction.Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells Genetic disruption of SOD1 gene causes glucose intolerance and impairs β-cell function.Serum Zn/Cu Ratio Is Associated with Renal Function, Glycemic Control, and Metabolic Parameters in Japanese Patients with and without Type 2 Diabetes: A Cross-sectional Study.Glutathione peroxidase mimic ebselen improves glucose-stimulated insulin secretion in murine islets Reappraisal of xenobiotic-induced, oxidative stress-mediated cellular injury in chronic pancreatitis: a systematic review.Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent Ebselen pretreatment attenuates ischemia/reperfusion injury and prevents hyperglycemia by improving hepatic insulin signaling and β-cell survival in gerbils.Glutathionyl systems and metabolic dysfunction in obesity.Omega-3 fatty acids control productions of superoxide and nitrogen oxide and insulin content in INS-1E cells.The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system.Oxygen-dependent activation of Cu,Zn-superoxide dismutase-1.Cu,Zn-SOD deficiency induces the accumulation of hepatic collagen.

P2860

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P2860

Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity

http://www.wikidata.org/entity/Q34519502

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Antioxidants & Redox Signaling

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Knockouts of SOD1 and GPX1 exe ...... ction and pancreatic integrity

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Carol A Roneker

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Liangbiao G Hu

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Marko Z Vatamaniuk

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Matthew P Pepper

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Rebecca A Simmons

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Xiaodan Wang

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Xin Gen Lei

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P2860

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity

Reactive oxygen species have a causal role in multiple forms of insulin resistance

Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade.

A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity.

Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells.

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.

Pdx1 restores beta cell function in Irs2 knockout mice.

Role of copper,zinc-superoxide dismutase in catalyzing nitrotyrosine formation in murine liver.

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10.1089/ARS.2010.3302

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3

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14

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44850768

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20586612

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3026657

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