The emerging roles of translation factor eIF4E in the nucleus.
about
The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growthTracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4EmTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4ECandidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory proteinA role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies.Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localizationSimulation of non-specific protein-mRNA interactions.Mnk kinase pathway: Cellular functions and biological outcomeseIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTRPondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon?Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancerPondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies.Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA capEukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels.The translation initiation factor eIF4E regulates the sex-specific expression of the master switch gene Sxl in Drosophila melanogaster.eIF4E isoform 2 in Schizosaccharomyces pombe is a novel stress-response factor.Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer.Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis.Regulation of mammalian translation factors by nutrients.Cap-free structure of eIF4E suggests a basis for conformational regulation by its ligands.Visualization of the interaction between the precursors of VPg, the viral protein linked to the genome of turnip mosaic virus, and the translation eukaryotic initiation factor iso 4E in PlantaSmall-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue.eIF4E is a central node of an RNA regulon that governs cellular proliferation.Identification of a novel RNA giant nuclear body in cancer cells.Immunohistochemical expression of promyelocytic leukemia body in soft tissue sarcomasEukaryotic initiation factors (eIF) 2alpha and 4E expression, localization, and phosphorylation in brain tumorsCup is a nucleocytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development.Eukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond.The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled.Stopped-flow kinetic analysis of eIF4E and phosphorylated eIF4E binding to cap analogs and capped oligoribonucleotides: evidence for a one-step binding mechanism.Gamma interferon and cadmium treatments modulate eukaryotic initiation factor 4E-dependent mRNA transport of cyclin D1 in a PML-dependent manner.Activation of p53 stimulates proteasome-dependent truncation of eIF4E-binding protein 1 (4E-BP1).Features in the N and C termini of the MAPK-interacting kinase Mnk1 mediate its nucleocytoplasmic shuttling.Translation factor eIF4E rescues cells from Myc-dependent apoptosis by inhibiting cytochrome c release.Pharmacological targeting of eIF4E in primary CLL lymphocytes.The poly(A) binding protein is internalized in virus-induced vesicles or redistributed to the nucleolus during turnip mosaic virus infection.Understanding and Targeting the Eukaryotic Translation Initiation Factor eIF4E in Head and Neck Cancer.Association of ribosomal proteins with nascent transcripts in S. cerevisiae.The eukaryotic translation initiation factor 4E controls lettuce susceptibility to the Potyvirus Lettuce mosaic virus.
P2860
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P2860
The emerging roles of translation factor eIF4E in the nucleus.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The emerging roles of translation factor eIF4E in the nucleus.
@ast
The emerging roles of translation factor eIF4E in the nucleus.
@en
The emerging roles of translation factor eIF4E in the nucleus.
@nl
type
label
The emerging roles of translation factor eIF4E in the nucleus.
@ast
The emerging roles of translation factor eIF4E in the nucleus.
@en
The emerging roles of translation factor eIF4E in the nucleus.
@nl
prefLabel
The emerging roles of translation factor eIF4E in the nucleus.
@ast
The emerging roles of translation factor eIF4E in the nucleus.
@en
The emerging roles of translation factor eIF4E in the nucleus.
@nl
P1433
P1476
The emerging roles of translation factor eIF4E in the nucleus.
@en
P2093
Katherine L B Borden
Stephen Strudwick
P356
10.1046/J.1432-0436.2002.700102.X
P577
2002-03-01T00:00:00Z