Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation.
about
MHC class II transactivator represses human IL-4 gene transcription by interruption of promoter binding with CBP/p300, STAT6 and NFAT1 via histone hypoacetylationFOXP3 ensembles in T-cell regulationFOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repressionThe transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genesT-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-siteEpigenetic regulation in allergic diseases and related studiesT cell metabolism drives immunity1-Methyl-tryptophan can interfere with TLR signaling in dendritic cells independently of IDO activityEssential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene lociInterleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR)Clinical implications of interferon-γ genetic and epigenetic variantsEnvironmental epigenetics of asthma: an updateEpigenetics: connecting environment and genotype to phenotype and diseaseEnvironmental alkylphenols modulate cytokine expression in plasmacytoid dendritic cells.HDAC4 is expressed on multiple T cell lineages but dispensable for their development and function.The influence of dietary immunomodulatory factors on development of food allergy in childrenEffector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials.T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression.Self-antigen prevents CD8 T cell effector differentiation by CD134 and CD137 dual costimulation.Histone acetylation at the Ifng promoter in tolerized CD4 cells is associated with increased IFN-gamma expression during subsequent immunization to the same antigenTh2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthmaIgE regulates T helper cell differentiation through FcgammaRIII mediated dendritic cell cytokine modulation.Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.Cutting edge: the Th1 response inhibits the generation of peripheral regulatory T cells.Quantitative proteomics analysis of the nuclear fraction of human CD4+ cells in the early phases of IL-4-induced Th2 differentiation.Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cellsUpdate on allergies in pregnancy, lactation, and early childhood.Epigenetics and T-cell immunity.Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation.Maternal allergy increases susceptibility to offspring allergy in association with TH2-biased epigenetic alterations in a mouse model of peanut allergyThe interface between transcriptional and epigenetic control of effector and memory CD8⁺ T-cell differentiationEpigenetic regulation of beta2-adrenergic receptor expression in T(H)1 and T(H)2 cells.Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B).Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggressionEpigenetic control of gene expression in the lung.Dynamic BRG1 recruitment during T helper differentiation and activation reveals distal regulatory elements.An epigenetic view of helper T cell differentiation.CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BETCell-cycle regulation of T-cell responses--novel approaches to the control of alloimmunity.Epigenetic manipulation restores functions of defective CD8⁺ T cells from chronic viral infection
P2860
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P2860
Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@ast
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@en
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@nl
type
label
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@ast
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@en
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@nl
prefLabel
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@ast
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@en
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@nl
P2093
P1476
Cutting edge: changes in histo ...... mpany Th1/Th2 differentiation.
@en
P2093
Patrick E Fields
Richard A Flavell
Sean T Kim
P304
P356
10.4049/JIMMUNOL.169.2.647
P407
P577
2002-07-01T00:00:00Z