Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease.
about
Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategiesUncovering viral protein-protein interactions and their role in arenavirus life cycleReporter-Expressing, Replicating-Competent Recombinant ArenavirusesAnimal Models for the Study of Rodent-Borne Hemorrhagic Fever Viruses: Arenaviruses and HantavirusesJunín virus pathogenesis and virus replicationThe Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ ReceptorEpidemiology and pathogenesis of Bolivian hemorrhagic fever.Potent inhibition of Junín virus infection by interferon in murine cells.Endothelial cell permeability and adherens junction disruption induced by junín virus infectionComparative analysis of disease pathogenesis and molecular mechanisms of New World and Old World arenavirus infections.Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses.The curious case of arenavirus entry, and its inhibition.Development of live-attenuated arenavirus vaccines based on codon deoptimizationThe glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.Identification and Mechanism of Action of a Novel Small-Molecule Inhibitor of Arenavirus Multiplication.Machupo Virus Expressing GPC of the Candid#1 Vaccine Strain of Junin Virus Is Highly Attenuated and Immunogenic.Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever virusesArenavirus reverse genetics for vaccine developmentMyristoylation of the Arenavirus Envelope Glycoprotein Stable Signal Peptide Is Critical for Membrane Fusion but Dispensable for Virion MorphogenesisMice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virusReverse Genetics Approaches to Control Arenavirus.Rescue of a recombinant Machupo virus from cloned cDNAs and in vivo characterization in interferon (αβ/γ) receptor double knockout miceHost cell factors as antiviral targets in arenavirus infection.Current drug discovery strategies against arenavirus infections.Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression.Novel strategies for development of hemorrhagic fever arenavirus live-attenuated vaccines.Vaccine platforms to control Lassa fever.Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor.Differential Immune Responses to New World and Old World Mammalian Arenaviruses.Substitutions in the glycoprotein (GP) of the Candid#1 vaccine strain of Junin virus increase dependence on human transferrin receptor 1 for entry and destabilize the metastable conformation of GPLassa Virus Reverse Genetics.Arenavirus Genome Rearrangement for the Development of Live Attenuated Vaccines.A substitution in the transmembrane region of the glycoprotein leads to an unstable attenuation of Machupo virus.Determining the Virus Life-Cycle Stage Blocked by an Antiviral.Epistastic interactions within the Junín virus envelope glycoprotein complex provide an evolutionary barrier to reversion in the live-attenuated Candid#1 vaccine.The use of novel epitope-tagged arenaviruses reveals that Rab5c-positive endosomal membranes are targeted by the LCMV matrix protein.Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses.Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses.Description and characterization of a novel live-attenuated tri-segmented Machupo virus in Guinea pigs.
P2860
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P2860
Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@ast
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@en
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@nl
type
label
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@ast
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@en
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@nl
prefLabel
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@ast
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@en
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@nl
P2093
P2860
P356
P1433
P1476
Rescue from cloned cDNAs and i ...... ine hemorrhagic fever disease.
@en
P2093
Aida G Walker
Alexey V Seregin
Allison L Poussard
Juan C de la Torre
Nadezhda E Yun
Sebastien F Emonet
Slobodan Paessler
P2860
P304
P356
10.1128/JVI.02102-10
P407
P577
2010-12-01T00:00:00Z