A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation. - Wikidata - awgldk - TriplyDB

A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation.

A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation.

http://www.wikidata.org/entity/Q34532224

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Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress Retinal pathology and skin barrier defect in mice carrying a Stargardt disease-3 mutation in elongase of very long chain fatty acids-4 The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults Clinical applications of fundus autofluorescence in retinal disease Nrf2 Is an Attractive Therapeutic Target for Retinal Diseases Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo Immunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells.Phospholipid meets all-trans-retinal: the making of RPE bisretinoids Photooxidation of RPE lipofuscin bisretinoids enhances fluorescence intensity.Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation Synthesis of antioxidants for prevention of age-related macular degeneration Spatial localization of A2E in the retinal pigment epithelium Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration Post-translational protein modification by carotenoid cleavage products.Effects of organic solvents on two retinal pigment epithelial lipofuscin fluorophores, A2E and all-trans-retinal dimer Resveratrol protects human lens epithelial cells against H2O2-induced oxidative stress by increasing catalase, SOD-1, and HO-1 expression.The Benefits of Calorie Restriction and Calorie Restriction Mimetics as Related to the Eye.Evolution of the vertebrate pineal gland: the AANAT hypothesis.C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of Stargardt disease.Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial Involvement of c-Abl, p53 and the MAP kinase JNK in the cell death program initiated in A2E-laden ARPE-19 cells by exposure to blue light Light filtering in a retinal pigment epithelial cell culture model.Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits.Anatomic alterations in aging and age-related diseases of the eye.Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium Neurotrophins enhance retinal pigment epithelial cell survival through neuroprotectin D1 signaling Toward an understanding of bisretinoid autofluorescence bleaching and recovery ABCA4 mutations and discordant ABCA4 alleles in patients and siblings with bull's-eye maculopathy Blue-Light Filtering Spectacle Lenses: Optical and Clinical Performances The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model.Photodecomposition and phototoxicity of natural retinoids.Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents Mechanisms involved in A2E oxidation.New therapeutic targets in atrophic age-related macular degeneration.The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells Vitamin A-aldehyde adducts: AMD risk and targeted therapeutics.(R)-alpha-lipoic acid protects retinal pigment epithelial cells from oxidative damage.Photodegradation of retinal bisretinoids in mouse models and implications for macular degeneration Neurotrophins induce neuroprotective signaling in the retinal pigment epithelial cell by activating the synthesis of the anti-inflammatory and anti-apoptotic neuroprotectin D1.Resveratrol prevents antibody-induced apoptotic death of retinal cells through upregulation of Sirt1 and Ku70

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P2860

A2E-epoxides damage DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation.

http://www.wikidata.org/entity/Q34532224

description

2003 nî lūn-bûn

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2003 թուականի Մարտին հրատարակուած գիտական յօդուած

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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type

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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A2E-epoxides damage DNA in ret ...... inhibit A2E-epoxide formation.

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P2093

Heidi R Vollmer-Snarr

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Janet R Sparrow

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Jilin Zhou

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Steffen Jockusch

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Yasuhiro Itagaki

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P2860

The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma

A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8

Structural refinement of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy-aflatoxin B(1) adduct in a 5'-Cp(AFB)G-3' sequence

No truth to the fountain of youth

Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium

A simple technique for quantitation of low levels of DNA damage in individual cells

Single cell gel electrophoresis assay: methodology and applications

Synthesis, characterization, and applications of a fluorescent probe of DNA damage.

Patterns of increased in vivo fundus autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration.

A test of the singlet oxygen mechanism of cationic dye photosensitization of mitochondrial damage.

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18207-18213

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10.1074/JBC.M300457200

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20

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278

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12646558

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