Vibrio vulnificus rtxA1 gene recombination generates toxin variants with altered potency during intestinal infection
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Multifunctional-autoprocessing repeats-in-toxin (MARTX) Toxins of VibriosMARTX toxins as effector delivery platformsVibrio vulnificus Type 6 Secretion System 1 Contains Anti-Bacterial PropertiesCytotoxicity of the Vibrio vulnificus MARTX toxin effector DUF5 is linked to the C2A subdomain.Analysis of Vibrio cholerae genome sequences reveals unique rtxA variants in environmental strains and an rtxA-null mutation in recent altered El Tor isolates.Vibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in miceSurface hypothermia predicts murine mortality in the intragastric Vibrio vulnificus infection modelIn vivo efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus sepsis.Additive function of Vibrio vulnificus MARTX(Vv) and VvhA cytolysins promotes rapid growth and epithelial tissue necrosis during intestinal infection.Comparison of Xenorhabdus bovienii bacterial strain genomes reveals diversity in symbiotic functions.Monoclonal antibodies against Vibrio vulnificus RtxA1 elicit protective immunity through distinct mechanisms.Draft Genome Sequences of Four Closely Linked Vibrio vulnificus Isolates from the Biotype 1 Environmental GenotypeSite-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain.Vibrio cholerae MARTX toxin heterologous translocation of beta-lactamase and roles of individual effector domains on cytoskeleton dynamics.Distinct roles of the repeat-containing regions and effector domains of the Vibrio vulnificus multifunctional-autoprocessing repeats-in-toxin (MARTX) toxin.Sialic acid catabolism and transport gene clusters are lineage specific in Vibrio vulnificusInduced autoprocessing of the cytopathic Makes caterpillars floppy-like effector domain of the Vibrio vulnificus MARTX toxin.The Makes Caterpillars Floppy (MCF)-Like Domain of Vibrio vulnificus Induces Mitochondrion-Mediated ApoptosisActin cross-linking domain of Aeromonas hydrophila repeat in toxin A (RtxA) induces host cell rounding and apoptosis.Abundant toxin-related genes in the genomes of beneficial symbionts from deep-sea hydrothermal vent mussels.Vibrio vulnificus: From Oyster Colonist to Human Pathogen.The Effector Domain Region of the Vibrio vulnificus MARTX Toxin Confers Biphasic Epithelial Barrier Disruption and Is Essential for Systemic Spread from the IntestineThe regulator HlyU, the repeat-in-toxin gene rtxA1, and their roles in the pathogenesis of Vibrio vulnificus infectionsIdentification of a His-Asp-Cys catalytic triad essential for function of the Rho inactivation domain (RID) of Vibrio cholerae MARTX toxin.The fur-iron complex modulates expression of the quorum-sensing master regulator, SmcR, to control expression of virulence factors in Vibrio vulnificus.Vibrio vulnificus: death on the half shell. A personal journey with the pathogen and its ecology.Pathogenic Mechanisms of Actin Cross-Linking Toxins: Peeling Away the Layers.MARTX of Vibrio vulnificus biotype 2 is a virulence and survival factor.Variable Virulence of Biotype 3 Vibrio vulnificus due to MARTX Toxin Effector Domain Composition.Vibrio vulnificus MARTX cytotoxin causes inactivation of phagocytosis-related signaling molecules in macrophages.MARTX effector cross kingdom activation by Golgi-associated ADP-ribosylation factors.MARTX Toxin in the Zoonotic Serovar of Vibrio vulnificus Triggers an Early Cytokine Storm in Mice.IutB participates in the ferric-vulnibactin utilization system in Vibrio vulnificus M2799.Development and characterization of a catalytically inactive cysteine protease domain of RtxA1/MARTXVv as a potential vaccine for Vibrio vulnificus.Characterization of Prohibitin 1 as a Host Partner of Vibrio vulnificus RtxA1 Toxin.Genetic characterization of Vibrio vulnificus strains isolated from oyster samples in Mexico.Efficacy of Ceftriaxone, Cefepime, Doxycycline, Ciprofloxacin, and Combination Therapy for Vibrio vulnificus Foodborne Septicemia.Nε-Fatty acylation of Rho GTPases by a MARTX toxin effector.Coordinated delivery and function of bacterial MARTX toxin effectors.Wild eel microbiome reveals that skin mucus of fish could be a natural niche for aquatic mucosal pathogen evolution.
P2860
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P2860
Vibrio vulnificus rtxA1 gene recombination generates toxin variants with altered potency during intestinal infection
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2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2011 թվականի հունվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@ast
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@en
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@nl
type
label
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@ast
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@en
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@nl
prefLabel
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@ast
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@en
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@nl
P2860
P356
P1476
Vibrio vulnificus rtxA1 gene r ...... cy during intestinal infection
@en
P2093
Jayme S Kwak
Karla J F Satchell
P2860
P304
P356
10.1073/PNAS.1014339108
P407
P50
P577
2011-01-10T00:00:00Z