The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.

The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.

Item
http://www.wikidata.org/entity/Q34534031
Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer.Estrogen receptors in breast and bone: from virtue of remodeling to vileness of metastasis.The Evolving Role of the Estrogen Receptor Mutations in Endocrine Therapy-Resistant Breast Cancer.18F-Fluoroestradiol PET/CT Measurement of Estrogen Receptor Suppression during a Phase I Trial of the Novel Estrogen Receptor-Targeted Therapeutic GDC-0810: Using an Imaging Biomarker to Guide Drug Dosage in Subsequent Trials.Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers.Are We Ready to Use ESR1 Mutations in Clinical Practice?Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets.Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity.
P2860

The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.

Item
http://www.wikidata.org/entity/Q34534031
description
2016 nî lūn-bûn
@nan
2016 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2016年の論文
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2016年論文
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2016年論文
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2016年論文
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2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
The selective estrogen recepto ...... e models of ER+ breast cancer.
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The selective estrogen recepto ...... e models of ER+ breast cancer.
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The selective estrogen recepto ...... e models of ER+ breast cancer.
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type
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The selective estrogen recepto ...... e models of ER+ breast cancer.
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The selective estrogen recepto ...... e models of ER+ breast cancer.
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The selective estrogen recepto ...... e models of ER+ breast cancer.
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The selective estrogen recepto ...... e models of ER+ breast cancer.
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The selective estrogen recepto ...... e models of ER+ breast cancer.
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The selective estrogen recepto ...... e models of ER+ breast cancer.
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P1433
P1476
P2093
P2860
P31
P356
P407
P478
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P1476
The selective estrogen recepto ...... se models of ER+ breast cancer
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P2093
P2860
P31
P356
P407
P478
P50
P577
P698
P932