Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
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Viral Infections and Obesity.Gut-Brain Cross-Talk in Metabolic Control.Hypothalamic circuits regulating appetite and energy homeostasis: pathways to obesity.Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity.A Macrocyclic Agouti-Related Protein/[Nle4,DPhe7]α-Melanocyte Stimulating Hormone Chimeric Scaffold Produces Subnanomolar Melanocortin Receptor Ligands.From Bioinactive ACTH to ACTH Antagonist: The Clinical Perspective.Suppressed sympathetic outflow to skeletal muscle, muscle thermogenesis, and activity energy expenditure with calorie restriction.Melanocortin-4 Receptor Gene Mutations in a Group of Turkish Obese Children and Adolescents.Genetics of obesity: can an old dog teach us new tricks?Role of the brain melanocortins in blood pressure regulation.Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016.Medication use for the treatment of diabetes in obese individuals.Interactome of Obesity: Obesidome : Genetic Obesity, Stress Induced Obesity, Pathogenic Obesity Interaction.Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout miceGene-nutrient interactions and susceptibility to human obesity.Estimated prevalence of potentially damaging variants in the leptin gene.Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field.Molecular Therapy of Melanocortin-4-Receptor Obesity by an Autoregulatory BDNF Vector.Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations.Cannabis in fat: high hopes to treat obesity.The current state of GPCR-based drug discovery to treat metabolic disease.Genetic and Syndromic Causes of Obesity and its Management.Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesity.Obesity Triggers: Sequencing the Genome Versus Sequencing the Environment.Toward Precision Approaches for the Prevention and Treatment of Obesity.Patient-Centered Reverse Translation.Early-Onset Obesity: Unrecognized First Evidence for GNAS Mutations and Methylation Changes.Neuroendocrinology: New hormone treatment for obesity caused by POMC-deficiency.Binding, Thermodynamics, and Selectivity of a Non-peptide Antagonist to the Melanocortin-4 Receptor.CoDE-seq, an augmented whole-exome sequencing, enables the accurate detection of CNVs and mutations in Mendelian obesity and intellectual disability.Centrally Acting Agents for Obesity: Past, Present, and Future
P2860
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P2860
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
description
2016 nî lūn-bûn
@nan
2016 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@ast
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@en
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@nl
type
label
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@ast
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@en
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@nl
prefLabel
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@ast
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@en
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@nl
P2093
P50
P356
P1476
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
@en
P2093
Annette Grüters
Heiko Krude
Keith Gottesdiener
Lea L Martini
Oliver Blankenstein
Peter Kühnen
Ulrike Blume-Peytavi
P304
P356
10.1056/NEJMOA1512693
P407
P577
2016-07-01T00:00:00Z