Indicators of marginal biotin deficiency and repletion in humans: validation of 3-hydroxyisovaleric acid excretion and a leucine challenge.
about
Biotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood.Novel roles of holocarboxylase synthetase in gene regulation and intermediary metabolismBiotinUrinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humansLymphocyte propionyl-CoA carboxylase and its activation by biotin are sensitive indicators of marginal biotin deficiency in humansDevelopment and characterization of a mouse with profound biotinidase deficiency: a biotin-responsive neurocutaneous disorderBiotin requirements are lower in human Jurkat lymphoid cells but homeostatic mechanisms are similar to those of HepG2 liver cells.Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.Marginal maternal biotin deficiency in CD-1 mice reduces fetal mass of biotin-dependent carboxylasesIncreasing longevity by tuning up metabolism. To maximize human health and lifespan, scientists must abandon outdated models of micronutrients.Marginal biotin deficiency during normal pregnancy.Marginal biotin deficiency is teratogenic in ICR mice.3-Hydroxypropionic acid and methylcitric acid are not reliable indicators of marginal biotin deficiency in humans.Smoking accelerates biotin catabolism in women.Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans.In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency.Marginal biotin deficiency can be induced experimentally in humans using a cost-effective outpatient design.Feeding Drosophila a biotin-deficient diet for multiple generations increases stress resistance and lifespan and alters gene expression and histone biotinylation patternsIdentification and assessment of markers of biotin status in healthy adults.Measurement of 3-hydroxyisovaleric acid in urine from marginally biotin-deficient humans by UPLC-MS/MSQuantitative measurement of urinary excretion of 3-hydroxyisovaleryl carnitine by LC-MS/MS as an indicator of biotin status in humansMarginal biotin deficiency is common in normal human pregnancy and is highly teratogenic in miceIntake and urinary amounts of biotin in Japanese elementary school children, college students, and elderly persons.Biotin: From Nutrition to Therapeutics.
P2860
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P2860
Indicators of marginal biotin deficiency and repletion in humans: validation of 3-hydroxyisovaleric acid excretion and a leucine challenge.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Indicators of marginal biotin ...... etion and a leucine challenge.
@ast
Indicators of marginal biotin ...... etion and a leucine challenge.
@en
Indicators of marginal biotin ...... etion and a leucine challenge.
@nl
type
label
Indicators of marginal biotin ...... etion and a leucine challenge.
@ast
Indicators of marginal biotin ...... etion and a leucine challenge.
@en
Indicators of marginal biotin ...... etion and a leucine challenge.
@nl
prefLabel
Indicators of marginal biotin ...... etion and a leucine challenge.
@ast
Indicators of marginal biotin ...... etion and a leucine challenge.
@en
Indicators of marginal biotin ...... etion and a leucine challenge.
@nl
P2093
P2860
P356
P1476
Indicators of marginal biotin ...... etion and a leucine challenge.
@en
P2093
Cindy L Henrich
Donald M Mock
Nadine Carnell
Nell I Mock
P2860
P304
P356
10.1093/AJCN/76.5.1061
P407
P577
2002-11-01T00:00:00Z