New determinants of receptor-effector coupling: trafficking and compartmentation in membrane microdomains.
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Signaling and regulation of G protein-coupled receptors in airway smooth muscleGialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptorsDisruption of lipid rafts inhibits P2X1 receptor-mediated currents and arterial vasoconstrictionSchizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo.Signaling epicenters: the role of caveolae and caveolins in volatile anesthetic induced cardiac protection.Caveolae structure and functionHuman bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains.Regulation of growth factor receptors by gangliosides.Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy.Adenylyl cyclase 2 selectively couples to E prostanoid type 2 receptors, whereas adenylyl cyclase 3 is not receptor-regulated in airway smooth muscle.Caveolins: targeting pro-survival signaling in the heart and brain.The association of caveolae, actin, and the dystrophin-glycoprotein complex: a role in smooth muscle phenotype and function?Regulation of heterotrimeric G protein signaling in airway smooth muscle.Caveolin-1 Regulates the P2Y2 Receptor Signaling in Human 1321N1 Astrocytoma Cells.Clozapine, atypical antipsychotics, and the benefits of fast-off D2 dopamine receptor antagonism.Integrin signaling in inflammatory and neuropathic pain in the rat.Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors.Agonist-selective dynamic compartmentalization of human Mu opioid receptor as revealed by resolutive FRAP analysis.Different phospholipase-C-coupled receptors differentially regulate capacitative and non-capacitative Ca2+ entry in A7r5 cells.Visualization of G protein betagamma dimers using bimolecular fluorescence complementation demonstrates roles for both beta and gamma in subcellular targeting.Expression levels strongly affect ligand-induced sequestration of B2 bradykinin receptors in transfected cells.Endogenous RGS protein action modulates mu-opioid signaling through Galphao. Effects on adenylyl cyclase, extracellular signal-regulated kinases, and intracellular calcium pathways.Immunolocalization and expression of kinin B1R and B2R receptors in human inflammatory bowel disease.The kallikrein-kinin system in experimental Chagas disease: a paradigm to investigate the impact of inflammatory edema on GPCR-mediated pathways of host cell invasion by Trypanosoma cruzi.Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins.A fluorescence resonance energy transfer-based sensor indicates that receptor access to a G protein is unrestricted in a living mammalian cell.Parameters of drug antagonism: re-examination of two modes of functional competitive drug antagonism on intraocular muscles.The cholesterol-complexing agent digitonin modulates ligand binding of the bovine hippocampal serotonin 1A receptor.ATP inhibits Ins(1,4,5)P3-evoked Ca2+ release in smooth muscle via P2Y1 receptors.Assessment of de novo copy-number variations in Italian patients with schizophrenia: Detection of putative mutations involving regulatory enhancer elements.Collateral efficacy as a pharmacological problem applied to new drug discovery.Role of caveolae in ouabain-induced proliferation of cultured vascular smooth muscle cells of the synthetic phenotypeSignaling and regulation of G protein-coupled receptors in airway smooth muscle
P2860
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P2860
New determinants of receptor-effector coupling: trafficking and compartmentation in membrane microdomains.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
New determinants of receptor-e ...... tion in membrane microdomains.
@ast
New determinants of receptor-e ...... tion in membrane microdomains.
@en
New determinants of receptor-e ...... tion in membrane microdomains.
@nl
type
label
New determinants of receptor-e ...... tion in membrane microdomains.
@ast
New determinants of receptor-e ...... tion in membrane microdomains.
@en
New determinants of receptor-e ...... tion in membrane microdomains.
@nl
prefLabel
New determinants of receptor-e ...... tion in membrane microdomains.
@ast
New determinants of receptor-e ...... tion in membrane microdomains.
@en
New determinants of receptor-e ...... tion in membrane microdomains.
@nl
P356
P1476
New determinants of receptor-e ...... ation in membrane microdomains
@en
P2093
Rennolds S Ostrom
P304
P356
10.1124/MOL.61.3.473
P577
2002-03-01T00:00:00Z