The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20.
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New and emerging disease modifying therapies for multiple sclerosisOfatumumab for rheumatoid arthritisRituximab, ofatumumab and other monoclonal anti-CD20 antibodies for chronic lymphocytic leukaemiaOfatumumab: a novel monoclonal anti-CD20 antibodyThe role of ofatumumab in the treatment of chronic lymphocytic leukemia resistant to previous therapiesThe emerging role of ofatumumab in the treatment of chronic lymphocytic leukemiaOfatumumabAn update on the evidence for the efficacy and safety of rituximab in the management of neuromyelitis opticaImmunotherapy in Chronic Lymphocytic Leukaemia (CLL)New developments in the management of chronic lymphocytic leukemia: role of ofatumumabLessons for the clinic from rituximab pharmacokinetics and pharmacodynamicsNew antibody approaches to lymphoma therapyMonoclonal antibodies for the treatment of cancerStructural basis for recognition of CD20 by therapeutic antibody RituximabChronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatmentStatins impair antitumor effects of rituximab by inducing conformational changes of CD20Affinity is an important determinant of the anti-trypanosome activity of nanobodiesIbrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy.Complement dependent cytotoxicity in chronic lymphocytic leukemia: ofatumumab enhances alemtuzumab complement dependent cytotoxicity and reveals cells resistant to activated complement.In silico designing, cloning, and heterologous expression of novel chimeric human B lymphocyte CD20 extra loop.Induced resistance to ofatumumab-mediated cell clearance mechanisms, including complement-dependent cytotoxicity, in chronic lymphocytic leukemia.Complement is activated by IgG hexamers assembled at the cell surface.Exhaustion of cytotoxic effector systems may limit monoclonal antibody-based immunotherapy in cancer patientsImmunotherapeutic mechanisms of anti-CD20 monoclonal antibodies.NK-cell activation and antibody-dependent cellular cytotoxicity induced by rituximab-coated target cells is inhibited by the C3b component of complement.Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca(2+) influx and induces streamers.Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies.Preserved Activity of CD20-Specific Chimeric Antigen Receptor-Expressing T Cells in the Presence of Rituximab.Synthetic antibodies as therapeutics.Chemoimmunotherapy with O-FC in previously untreated patients with chronic lymphocytic leukemia.The use of monoclonal antibodies in the treatment of autoimmune complications of chronic lymphocytic leukemia.A multicentre, phase II trial of ofatumumab monotherapy in relapsed/progressive diffuse large B-cell lymphoma.Ofatumumab in poor-prognosis chronic lymphocytic leukemia: a phase IV, non-interventional, observational study from the European Research Initiative on Chronic Lymphocytic Leukemia.The clinical development of obinutuzumab for the treatment of follicular lymphoma.A novel human anti-interleukin-1β neutralizing monoclonal antibody showing in vivo efficacyManagement of chronic lymphocytic leukemia.Prevention trumps treatment of antibody-mediated transplant rejectionRobust memory responses against influenza vaccination in pemphigus patients previously treated with rituximabIncreasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicityFunctional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4
P2860
Q22242305-CD4DDA8C-2500-45AF-8CF9-4CA2CCACAC04Q24202719-708313AC-A5D3-4071-9AA0-E2CE536102BEQ24203027-D167D223-DC92-4756-8C91-1E8AA18726DBQ24604065-82113206-99ED-491D-A099-61B4504DEF6FQ24605471-EDC952FE-EEB9-423B-9758-18765477F183Q24617708-95C66391-5578-4EDC-819E-A7F633890F87Q24651912-2D615461-1187-4C70-90B3-A933184F65B5Q26748601-0467FCAD-F868-4C33-A882-7CB49518A68DQ26768154-CF4EEE7A-601C-49BE-83E5-7ADD793599C8Q26768396-18487725-1ED9-48C3-871D-4ECD8035F8F0Q26849243-D4C100D4-0480-4DD1-B6C0-AB59F7FA9530Q27022373-C5FC062A-18C4-4C4A-892F-02513CBCB54EQ27025966-C0BCD45A-9EDA-4371-B633-D2929B3057DCQ27644280-68D4CE48-302C-4151-82E3-02B039B02EA2Q28082086-A3A34B5E-FDB5-4F26-8DF4-80FCBE7DB9F3Q28472420-612700E5-147C-4F72-A3B0-C892275E129DQ28485195-2B0233CF-096C-4A51-B5DF-89DDF0C3F49EQ30303054-9C1B1252-128E-4AED-BD00-6FF55052268EQ30356145-6F00584F-4FD5-424E-91E5-8390E643D207Q30389864-52A9E0B3-C4CE-499F-8EDC-D05B88D2590DQ30405847-27CEA307-3D6C-4C53-BF5F-5BEC3388CB63Q30409381-C8CACE6A-3B04-4135-9F6C-262771F831D4Q30421637-8AD1DB64-D85C-4E45-8451-E8AF821B9F91Q30439017-4DEE5F76-760D-4737-98FC-19889A9B8021Q30440293-21CBC380-1BC4-4208-B6E0-53E5E88A7286Q30453680-0829027D-78F4-45BD-9F5E-C77C970AAA4CQ30500362-C3525336-BFA7-4890-8719-9D20AC874069Q30764873-342D4B27-D085-4623-83B4-0A2C4C7DD66AQ33265617-E1D7E670-4764-46E4-B3D3-8936DED6F347Q33394947-7E7BDC39-285B-474D-AC36-08CA0F920A31Q33407700-FF98E85D-E8D9-43F4-8F4C-92ACD7AB4109Q33410306-3759C33B-A388-4247-BA76-40F0D9A0C5CEQ33419843-2E13EB0E-474B-4BA9-8D4A-EF1A4865BD54Q33565265-FDA531B4-BB9F-4370-B702-F2161D6FE73FQ33573612-9DACFA14-826A-48ED-A365-2968BD987BCCQ33695912-148D037E-1226-445E-A8BE-C246CE54EADDQ33755462-2A4DF0BC-1512-4B7F-95C6-8F14B890CD9DQ33798060-F3C391DB-FD35-4C4E-BF00-060356262809Q33896738-B95BD495-9D56-4EA1-A8CA-4A0C1E3938F2Q34055092-F67D6B5A-BF1B-4C99-8103-79EE428A3B0C
P2860
The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The biological activity of hum ...... ed to unique epitopes on CD20.
@ast
The biological activity of hum ...... ed to unique epitopes on CD20.
@en
The biological activity of hum ...... ed to unique epitopes on CD20.
@nl
type
label
The biological activity of hum ...... ed to unique epitopes on CD20.
@ast
The biological activity of hum ...... ed to unique epitopes on CD20.
@en
The biological activity of hum ...... ed to unique epitopes on CD20.
@nl
prefLabel
The biological activity of hum ...... ed to unique epitopes on CD20.
@ast
The biological activity of hum ...... ed to unique epitopes on CD20.
@en
The biological activity of hum ...... ed to unique epitopes on CD20.
@nl
P2093
P1476
The biological activity of hum ...... ed to unique epitopes on CD20.
@en
P2093
Jan G J van de Winkel
Jeroen H N van den Brakel
Jerry W Slootstra
Jessica L Teeling
Luus J J M Wiegman
Martin J Glennie
Paul W H I Parren
Ruth R French
Saskia Ebeling
Stephen A Beers
P304
P356
10.4049/JIMMUNOL.177.1.362
P407
P577
2006-07-01T00:00:00Z