Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
about
ATR suppresses endogenous DNA damage and allows completion of homologous recombination repairGenetic determinants and potential therapeutic targets for pancreatic adenocarcinomaScreening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individualsFIGNL1-containing protein complex is required for efficient homologous recombination repairChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repairEnhancement of RAD51 recombinase activity by the tumor suppressor PALB2.FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathwayA novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrityAPRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancerMRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaksA genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stabilityFANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repairHSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage responseStructural basis for recruitment of BRCA2 by PALB2PALB2 is an integral component of the BRCA complex required for homologous recombination repairPALB2 regulates recombinational repair through chromatin association and oligomerizationBreast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forksThe role of the human SWI5-MEI5 complex in homologous recombination repairBreast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repairHomologous recombination in DNA repair and DNA damage toleranceDynamics of DNA damage response proteins at DNA breaks: a focus on protein modificationsHomologous recombination research is heating up and ready for therapyPALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility geneMolecular pathogenesis and clinical management of Fanconi anemiaHow the fanconi anemia pathway guards the genomeExomic sequencing identifies PALB2 as a pancreatic cancer susceptibility geneAnalysis of PALB2/FANCN-associated breast cancer familiesIdentification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repairInterplay between Fanconi anemia and homologous recombination pathways in genome integrityExploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer TherapyThe expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2The Fanconi anemia pathway and DNA interstrand cross-link repairInteraction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2Exosomes-mediate microRNAs transfer in breast cancer chemoresistance regulationHomologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsMolding BRCA2 function through its interacting partnersNUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stabilityA comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assayUnraveling the mechanism of BRCA2 in homologous recombination
P2860
Q21090645-B7C08B14-57F7-4296-BA2A-917F83BD7927Q21129230-A7ABCF3A-98C9-4A06-8ADB-0C44ED2BD911Q22000758-3C68EF77-17A7-43B3-A609-135368FEC91EQ24294857-A65C09F2-E7F9-4C05-86BA-32087ECB667FQ24300467-C3AEFCF2-3405-46B3-A979-3A6F09892858Q24301052-D8B436E6-407C-43B9-A710-15E27209B0CEQ24301340-17533E35-86CE-485B-9519-EB004596BBAFQ24304112-F23F5BAD-5C0B-4318-A476-26ED624451F4Q24304176-8163AD4E-5950-442F-BC90-94E9EE99F9FEQ24304427-01CD418A-47C2-469C-9D6E-48DA904FC7ADQ24306107-1089184F-A149-47EB-8DFA-7939D0140AA0Q24307531-7ECB2A44-A266-4592-9B80-1C683D964752Q24314301-160CA50A-02DE-4964-A2AF-47CEC6058111Q24314871-19647DE4-806C-4568-994B-82BCEB75CD23Q24315745-BACF7E2C-08C5-464A-B7CC-56479908FC43Q24316113-3DC0D167-5108-4DA6-AA72-014DAAB4E520Q24322952-769B7F7E-6508-4156-8668-6C705F64CB8AQ24328790-F15D7CB0-547C-4FD2-B9DA-E4F9BE83BF8DQ24337776-93884F8F-7665-4DC2-A2CA-2F81D39F4E7FQ24338777-39BB2234-EE49-45A9-923D-020D9DF870DDQ24601150-DA812577-ADD4-4939-B3E2-D4F303436207Q24608343-B6A4DB5E-EBBC-4E35-AE93-73871814A51CQ24612269-1716C083-4115-4007-BC70-0BE8C747DBDCQ24615080-FB684F71-F39A-441F-ADA1-4B3AA99A13D0Q24621696-9FDADDF7-C9CF-4DBE-AF56-55D95CC77CA1Q24634556-94291CFC-3FD6-4FF2-833A-EDB283B1CC08Q24658271-46ADDF09-CCD7-4DDB-BE8D-D9F8F9D41D6CQ24683771-4C2764B3-4ECA-4CD6-9AF6-04BAD41389CFQ24685928-5D5289CE-B557-4D90-8DCF-8DB39E2A13CFQ26753126-98F1796B-C2B0-4B4E-9792-73F5731A9EFFQ26801593-3821DC8C-CE45-462B-9388-BC9F328E6644Q26851138-4A6887DB-7A53-4DC7-89CA-248CA26ADDEAQ26851561-9C860928-1187-4C8F-8C69-233BE87B2EE5Q27308072-25D1BC41-AA4C-49DA-91BA-2F79E2B59610Q28066991-9BCD7E6B-3267-40DF-A613-9B877A4BE75CQ28085364-EA00FA21-3996-447E-9F5D-5A7507A23939Q28085603-6C6ED1DA-805A-41AB-9389-9529CAF702AEQ28115978-6D44BD35-7376-42B7-A7B6-CAB409625532Q28118199-78C35746-DBF2-4E3A-AE74-A26A38B59A26Q28242443-2667D510-2286-47B5-89B4-69D61597E8FC
P2860
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@ast
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@en
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@nl
type
label
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@ast
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@en
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@nl
prefLabel
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@ast
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@en
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@nl
P2093
P1433
P1476
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
@en
P2093
Akihiro Ohashi
David M Livingston
Jianmin Wu
Koji Nakanishi
Maria Jasin
Nicole Christ
Qing Sheng
Xinggang Liu
P304
P356
10.1016/J.MOLCEL.2006.05.022
P577
2006-06-01T00:00:00Z