Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. - Wikidata - awgldk - TriplyDB

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

http://www.wikidata.org/entity/Q34541051

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ATR suppresses endogenous DNA damage and allows completion of homologous recombination repair Genetic determinants and potential therapeutic targets for pancreatic adenocarcinoma Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individuals FIGNL1-containing protein complex is required for efficient homologous recombination repair ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway A novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrity APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3 Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response Structural basis for recruitment of BRCA2 by PALB2 PALB2 is an integral component of the BRCA complex required for homologous recombination repair PALB2 regulates recombinational repair through chromatin association and oligomerization Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks The role of the human SWI5-MEI5 complex in homologous recombination repair Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair Homologous recombination in DNA repair and DNA damage tolerance Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Homologous recombination research is heating up and ready for therapy PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene Molecular pathogenesis and clinical management of Fanconi anemia How the fanconi anemia pathway guards the genome Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene Analysis of PALB2/FANCN-associated breast cancer families Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair Interplay between Fanconi anemia and homologous recombination pathways in genome integrity Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2 The Fanconi anemia pathway and DNA interstrand cross-link repair Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2 Exosomes-mediate microRNAs transfer in breast cancer chemoresistance regulation Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins Molding BRCA2 function through its interacting partners NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability A comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assay Unraveling the mechanism of BRCA2 in homologous recombination

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P2860

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

http://www.wikidata.org/entity/Q34541051

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006 թվականի հունիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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type

label

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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prefLabel

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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J.MOLCEL.2006.05.022

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Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

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P2093

Akihiro Ohashi

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Bing Xia

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David M Livingston

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Jianmin Wu

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Koji Nakanishi

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Maria Jasin

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Nicole Christ

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Qing Sheng

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Xinggang Liu

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719-729

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scholarly article

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10.1016/J.MOLCEL.2006.05.022

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6

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22

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Fergus J. Couch

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2006-06-01T00:00:00Z

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16793542

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