SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity - Wikidata - awgldk - TriplyDB

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

http://www.wikidata.org/entity/Q34542134

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Exogenous expression of SAMHD1 inhibits proliferation and induces apoptosis in cutaneous T-cell lymphoma-derived HuT78 cells.A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization, and Stability.Roles of SAMHD1 in antiviral defense, autoimmunity and cancer.Role of Innate Genes in HIV Replication.CD81 association with SAMHD1 enhances HIV-1 reverse transcription by increasing dNTP levels.SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.p21 Restricts HIV-1 in Monocyte-Derived Dendritic Cells through the Reduction of Deoxynucleoside Triphosphate Biosynthesis and Regulation of SAMHD1 Antiviral Activity.DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages.The Dynamic Interplay between HIV-1, SAMHD1, and the Innate Antiviral Response.The SAM domain of mouse SAMHD1 is critical for its activation and regulation.Interferons: Reprogramming the Metabolic Network against Viral Infection.A Cyclin-binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation.SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways.SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity.DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1.Reply to SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity.The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4+ T-cells.Prospects in Innate Immune Responses as Potential Control Strategies against Non-Primate Lentiviruses The role of SAMHD1 expression and its relation to HIV-2 (Vpx) gene production -Methyladenosine-binding proteins suppress HIV-1 infectivity and viral production

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SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

http://www.wikidata.org/entity/Q34542134

description

2016 nî lūn-bûn

@nan

2016 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

name

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@ast

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@en

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@nl

type

label

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@ast

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@en

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@nl

prefLabel

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@ast

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@en

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@nl

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Nature Medicine

P1476

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

@en

P2093

Baek Kim

http://www.w3.org/2001/XMLSchema#string

Caitlin Shepard

http://www.w3.org/2001/XMLSchema#string

Chenxiang Tang

http://www.w3.org/2001/XMLSchema#string

Corine St Gelais

http://www.w3.org/2001/XMLSchema#string

Jacob S Yount

http://www.w3.org/2001/XMLSchema#string

Jenna M Antonucci

http://www.w3.org/2001/XMLSchema#string

Suresh de Silva

http://www.w3.org/2001/XMLSchema#string

Xiaoyun Ji

http://www.w3.org/2001/XMLSchema#string

Yong Xiong

http://www.w3.org/2001/XMLSchema#string

P2860

Mechanism of allosteric activation of SAMHD1 by dGTP

Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

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1072-1074

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scholarly article

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10.1038/NM.4163

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P433

10

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22

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P577

2016-10-01T00:00:00Z

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27711056

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5069697

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