Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.
about
Pharmacogenetic studies update in type 2 diabetes mellitusThe role of drug transporters in the kidney: lessons from tenofovirOATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesRole of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacologyThe first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio).Structures of a Na+-coupled, substrate-bound MATE multidrug transporterStructural insights into H+-coupled multidrug extrusion by a MATE transporterRenal drug transporters and their significance in drug-drug interactionsCritical roles of Sp1 in gene expression of human and rat H+/organic cation antiporter MATE1Oppositely directed H+ gradient functions as a driving force of rat H+/organic cation antiporter MATE1Proton-dependent gating and proton uptake by Wzx support O-antigen-subunit antiport across the bacterial inner membraneA common 5'-UTR variant in MATE2-K is associated with poor response to metformin.Membrane transporters as mediators of Cisplatin effects and side effects.The Concise Guide to PHARMACOLOGY 2013/14: transporters.Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta-Analysis.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Molecular modeling and ligand docking for solute carrier (SLC) transportersChronic Kidney Disease and Exposure to Nephrotoxic MetalsDiscovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modelingAn update on the pharmacogenomics of metformin: progress, problems and potential.Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function.Exploring the transcriptome of ciliated cells using in silico dissection of human tissues.Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1Genetic variation in drug transporters in ethnic populations.Role of glutamate residues in substrate recognition by human MATE1 polyspecific H+/organic cation exporter.Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.Estradiol regulation of nucleotidases in female reproductive tract epithelial cells and fibroblasts.Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.Intake of St John's wort improves the glucose tolerance in healthy subjects who ingest metformin compared with metformin alone.Identification of functional amino acid residues involved in polyamine and agmatine transport by human organic cation transporter 2Large contiguous gene deletions in Sjögren-Larsson syndromeDeficiency of multidrug and toxin extrusion 1 enhances renal accumulation of paraquat and deteriorates kidney injury in mice.Contribution of tumoral and host solute carriers to clinical drug response.Electrophysiological characterization of the polyspecific organic cation transporter plasma membrane monoamine transporter.Molecular determinants of ligand selectivity for the human multidrug and toxin extruder proteins MATE1 and MATE2-K.Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory MechanismsTwelve transmembrane helices form the functional core of mammalian MATE1 (multidrug and toxin extruder 1) proteinAtenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins.Endocrine and metabolic regulation of renal drug transporters.
P2860
Q26739350-1D768999-5A33-40DE-9655-7F1187D3C4C2Q26866489-42B315F2-4C73-4416-92E2-ABBCAA8D171AQ27001267-D80FB696-A6D7-40C7-9D46-2027D0DADD72Q27026858-D23BAA37-7D76-40DF-B367-4808C25BF44FQ27334183-766C49B6-35A3-4991-A344-19C27202DEB7Q27675964-2585B3EE-912F-47DD-9350-75C68C7CD96FQ27680402-29124121-4F20-4A0C-A323-9A3853D11AD1Q28071292-50C97FF6-84F8-4791-95DA-71EED977AE10Q28248629-BFA9649A-3454-4A38-8472-01ED06500589Q28268920-F5A66D86-6777-46CE-9CB4-DAFF1D3EE515Q28492836-F2CEDFD9-8E6C-433E-8B1C-A49CA3561590Q30407583-8760D414-4523-417D-BF3C-E63FB8A474A5Q30446860-D01C9FC1-48B1-4AB1-A723-84313FD8AF82Q30486743-2E7641A4-42B5-4A81-8297-B7FE506A8297Q30571118-43E67066-3B51-41DA-B4E3-7218FBB98B7BQ33658321-23E7FC31-5A22-410B-933B-B82903623CDFQ33714593-3AD75F30-7899-4DCE-A4E7-8E3F40987803Q33751096-59FC05B0-B821-489D-974E-904C937DBCD0Q33755252-F5DFB599-AC62-4465-A9AF-84B61015427EQ33799288-C98C5E30-BB8E-4968-83B2-CA1F3E8C1D3FQ34003050-C9276340-E334-4C45-9BA3-2EFC4B5D7A8EQ34170589-9F5DDB2C-CD47-4E0C-AD49-B2E66307344CQ34256530-88A8DC31-4684-41E7-90BB-B328F3A42E6AQ34292530-177DDA34-6E81-4576-BD2F-EFA32088F527Q34292537-098AD6D8-C121-433B-AB65-C18C98BC3429Q34756325-BD2D0B87-369A-422F-9A02-4EC57FDCA058Q34777362-D6777EAB-4739-4A0F-8596-4CDA659243A9Q34921423-9A635CF8-840E-45E3-93A0-E2903F80D9F5Q35014972-CAD3CF50-0182-428E-AAF5-E0CFE3EDC8B4Q35023736-9C7D21CB-95E8-4034-9F85-BBC9FE31D3F8Q35206357-90A762AF-DC14-447E-8BA0-A3B746729ADFQ35387343-BB333AEB-7502-43E1-838B-EF3116D7A66DQ35591362-B7D7E57C-8EFA-4A51-AE86-B14768BE92CEQ35946876-D44231BD-F13A-4E6D-B813-BF3658571806Q35996455-FE1DD9A4-5C2B-4882-9DB0-141E08844A33Q35996683-A4D08190-CEEA-4610-BB3E-8FA4872825FDQ36017868-5F35D0A7-C668-467E-84E1-AE743758644FQ36201747-11E2B5DB-92D5-484A-AB70-83ED2C9DBDFBQ36316489-785FA1CB-3DAC-4DE7-A55A-2ECFBD0F12C0Q36335726-5F22D014-540C-412A-8CD9-35BA55A8215C
P2860
Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Identification and functional ...... ltidrug and toxin extrusion 2.
@ast
Identification and functional ...... ltidrug and toxin extrusion 2.
@en
Identification and functional ...... ltidrug and toxin extrusion 2.
@nl
type
label
Identification and functional ...... ltidrug and toxin extrusion 2.
@ast
Identification and functional ...... ltidrug and toxin extrusion 2.
@en
Identification and functional ...... ltidrug and toxin extrusion 2.
@nl
prefLabel
Identification and functional ...... ltidrug and toxin extrusion 2.
@ast
Identification and functional ...... ltidrug and toxin extrusion 2.
@en
Identification and functional ...... ltidrug and toxin extrusion 2.
@nl
P2093
P356
P1476
Identification and functional ...... ultidrug and toxin extrusion 2
@en
P2093
Ken-ichi Inui
Koshiro Kishimoto
Osamu Ogawa
Satohiro Masuda
Tomohiro Terada
Toshiya Katsura
Yuko Tanihara
P304
P356
10.1681/ASN.2006030205
P577
2006-06-28T00:00:00Z