MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer - Wikidata - awgldk - TriplyDB

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

http://www.wikidata.org/entity/Q34545271

about

MUTYH the base excision repair gene family member associated with colorectal cancer polyposis NOMO-1 gene is deleted in early-onset colorectal cancer.Early-onset colorectal cancer: a sporadic or inherited disease?Biallelic MUTYH mutations can mimic Lynch syndrome A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer.Functional analysis in mouse embryonic stem cells reveals wild-type activity for three MSH6 variants found in suspected Lynch syndrome patients.Multiple sporadic colorectal cancers display a unique methylation phenotype.Colorectal cancers with microsatellite instability display unique miRNA profiles.Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases.Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry Molecular Features and Methylation Status in Early Onset (≤40 Years) Colorectal Cancer: A Population Based, Case-Control Study.Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene.Whole exome sequencing and single nucleotide polymorphism array analyses to identify germline alterations in genes associated with testosterone metabolism in a patient with androgen insensitivity syndrome and early-onset colorectal cancer Early-onset colorectal cancer patients without family history are "at very low risk" for lynch syndrome.Contribution of bi-allelic germline MUTYH mutations to early-onset and familial colorectal cancer and to low number of adenomatous polyps: case-series and literature review.Colorectal cancer in young adults.Recommendations on Surveillance and Management of Biallelic Mismatch Repair Deficiency (BMMRD) Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer.Recent discoveries in the molecular genetics of Lynch syndrome.Clinicopathological characteristics of colorectal cancer presenting under the age of 50.ACMG technical standards and guidelines for genetic testing for inherited colorectal cancer (Lynch syndrome, familial adenomatous polyposis, and MYH-associated polyposis).Germline Genetic Features of Young Individuals with Colorectal Cancer.Colorectal cancer in patients under the age of 40 years: experience from a tertiary care centre in the Czech Republic.Prevalence and clinicopathologic/molecular characteristics of mismatch repair-deficient colorectal cancer in the under-50-year-old Japanese population.Deficient mismatch repair and RAS mutation in colorectal carcinoma patients: a retrospective study in Eastern China.

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MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

http://www.wikidata.org/entity/Q34545271

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

@ast

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

@en

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

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type

label

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

@ast

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

@en

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

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prefLabel

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

@ast

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

@en

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

@nl

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1078-0432.CCR-10-1491

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Clinical Cancer Research

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MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer

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Ajay Goel

http://www.w3.org/2001/XMLSchema#string

Anna Petit

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Antoni Castells

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C Richard Boland

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Francesc Balaguer

http://www.w3.org/2001/XMLSchema#string

Jenifer Muñoz

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José María Enríquez-Navascués

http://www.w3.org/2001/XMLSchema#string

Leticia Moreira

http://www.w3.org/2001/XMLSchema#string

Luis Bujanda

http://www.w3.org/2001/XMLSchema#string

María Dolores Giráldez

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P2860

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

Germline susceptibility to colorectal cancer due to base-excision repair gene defects.

Human non-synonymous SNPs: server and survey

Cancer statistics, 2009

Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.

Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.

Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).

A high incidence of MSH6 mutations in Amsterdam criteria II-negative families tested in a diagnostic setting.

Application of COLD-PCR for improved detection of KRAS mutations in clinical samples.

Family history and molecular features of children, adolescents, and young adults with colorectal carcinoma

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5402-5413

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scholarly article

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10.1158/1078-0432.CCR-10-1491

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22

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16

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2010-10-05T00:00:00Z

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47349584

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20924129

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colorectal cancer

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3032288

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