about
The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn diseaseStructure and mechanistic insights into novel iron-mediated moonlighting functions of human J-protein cochaperone, Dph4Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by HipBiological activities of HAP46/BAG-1. The HAP46/BAG-1 protein: regulator of HSP70 chaperones, DNA-binding protein and stimulator of transcription.Bleach activates a redox-regulated chaperone by oxidative protein unfoldingBAG-1 haplo-insufficiency impairs lung tumorigenesisTargeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseasesStructural Basis of J Cochaperone Binding and Regulation of Hsp70Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrateHsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions.A lysine-rich region within fungal BAG domain-containing proteins mediates a novel association with ribosomes.Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1.Substrate-binding domain conformational dynamics mediate Hsp70 allosteryIdentification of key hinge residues important for nucleotide-dependent allostery in E. coli Hsp70/DnaKHeat shock protein 70 interacts with aquaporin-2 and regulates its traffickingATP-induced conformational changes in Hsp70: molecular dynamics and experimental validation of an in silico predicted conformation.A genome-scale proteomic screen identifies a role for DnaK in chaperoning of polar autotransporters in Shigella.High affinity binding of hydrophobic and autoantigenic regions of proinsulin to the 70 kDa chaperone DnaK.Identification, characterization, and application of a recombinant antigen for the serological investigation of feline hemotropic Mycoplasma infections.Identification of regions involved in substrate binding and dimer stabilization within the central domains of yeast Hsp40 Sis1.Primate chaperones Hsc70 (constitutive) and Hsp70 (induced) differ functionally in supporting growth and prion propagation in Saccharomyces cerevisiae.Saccharomyces cerevisiae Hsp70 mutations affect [PSI+] prion propagation and cell growth differently and implicate Hsp40 and tetratricopeptide repeat cochaperones in impairment of [PSI+]PI3K-mTORC1 attenuates stress response by inhibiting cap-independent Hsp70 translation.Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperonesA model in which heat shock protein 90 targets protein-folding clefts: rationale for a new approach to neuroprotective treatment of protein folding diseasesImportance of the Hsp70 ATPase domain in yeast prion propagationAll in the family: atypical Hsp70 chaperones are conserved modulators of Hsp70 activity.Dancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins.Chaperone-assisted folding of newly synthesized proteins in the cytosol.Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and CommunicationA 70-kDa molecular chaperone, DnaK, from the industrial bacterium Bacillus licheniformis: gene cloning, purification and molecular characterization of the recombinant protein.Simian virus 40 T antigens and J domains: analysis of Hsp40 cochaperone functions in Escherichia coli.Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradationThe 70-kDa heat shock protein chaperone nucleotide-binding domain in solution unveiled as a molecular machine that can reorient its functional subdomains.HscA and HscB stimulate [2Fe-2S] cluster transfer from IscU to apoferredoxin in an ATP-dependent reaction.Multiple, but concerted cellular activities of the human protein Hap46/BAG-1M and isoforms.Free human mitochondrial GrpE is a symmetric dimer in solution.J domain independent functions of J proteins.mReg2 inhibits nuclear entry of apoptosis-inducing factor in mouse insulinoma cells.Molecular functions of Xanthomonas type III effector AvrBsT and its plant interactors in cell death and defense signaling.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Hsp70 chaperone machines.
@ast
Hsp70 chaperone machines.
@en
Hsp70 chaperone machines.
@nl
type
label
Hsp70 chaperone machines.
@ast
Hsp70 chaperone machines.
@en
Hsp70 chaperone machines.
@nl
prefLabel
Hsp70 chaperone machines.
@ast
Hsp70 chaperone machines.
@en
Hsp70 chaperone machines.
@nl
P1476
Hsp70 chaperone machines
@en
P2093
C S Gässler
P356
10.1016/S0065-3233(01)59001-4
P577
2001-01-01T00:00:00Z