Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans
about
Polymorphisms in the human cytochrome P450 and arylamine N-acetyltransferase: susceptibility to head and neck cancersFunctional evaluation of genetic and environmental regulators of p450 mRNA levelsVariability in drug metabolizing enzyme activity in HIV-infected patients.Lack of effect of chronic dextromethorphan on experimental pain tolerance in methadone-maintained patients.Cytochrome P450-2D6 extensive metabolizers are more vulnerable to methamphetamine-associated neurocognitive impairment: preliminary findings.Ontogeny of dextromethorphan O- and N-demethylation in the first year of life.Interpretation of mRNA splicing mutations in genetic disease: review of the literature and guidelines for information-theoretical analysis.Pharmacogenomics Implications of Using Herbal Medicinal Plants on African Populations in Health TransitionCYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele.Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects.Single dose, CYP2D6 genotype-stratified pharmacokinetic study of atomoxetine in children with ADHDCharacterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children.Cytochrome P450 2D6 polymorphisms and predicted opioid metabolism in African American children with sickle cell disease.Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity.Genetic polymorphism in cytochrome P450 2D6 (CYP2D6): Population distribution of CYP2D6 activity.Drug interactions in African herbal remedies.Polymorphic metabolism by functional alterations of human cytochrome P450 enzymes.Cytochrome P450 pharmacogenetics in African populations.Considerations for rare variants in drug metabolism genes and the clinical implications.Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing.Influence of the rs1080985 Single Nucleotide Polymorphism of the CYP2D6 Gene and APOE Polymorphism on the Response to Donepezil Treatment in Patients with Alzheimer's Disease in China.Resequencing, haplotype construction and identification of novel variants of CYP2D6 in Mexican Mestizos.CYP2D6 genetic variation in healthy adults and psychiatric African-American subjects: implications for clinical practice and genetic testing.Cytochrome P450-2D6*4 polymorphism seminal relationship in infertile men.Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.Full-gene haplotypes refine CYP2D6 metabolizer phenotype inferences.The CYP4502D6 *4 and *6 alleles are the molecular genetic markers for drug response: implications in colchicine non-responder FMF patients.Pharmacogenomics steps toward personalized medicineAnalysis of CYP2D6 Allele Frequencies and Identification of Novel SNPs and Sequence Variations in Sardinians
P2860
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P2860
Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Identification and characteriz ...... 2D6) gene in African Americans
@ast
Identification and characteriz ...... 2D6) gene in African Americans
@en
Identification and characteriz ...... ions in the cytochrome P4502D6
@nl
type
label
Identification and characteriz ...... 2D6) gene in African Americans
@ast
Identification and characteriz ...... 2D6) gene in African Americans
@en
Identification and characteriz ...... ions in the cytochrome P4502D6
@nl
prefLabel
Identification and characteriz ...... 2D6) gene in African Americans
@ast
Identification and characteriz ...... 2D6) gene in African Americans
@en
Identification and characteriz ...... ions in the cytochrome P4502D6
@nl
P2093
P2860
P356
P1476
Identification and characteriz ...... 2D6) gene in African Americans
@en
P2093
A Bhathena
J Steven Leeder
L DiAnne Bradford
L Ndjountché
R E Pearce
S M Abdel-Rahman
S W Alander
P2860
P2888
P304
P356
10.1038/SJ.TPJ.6500305
P577
2005-01-01T00:00:00Z
P5875
P6179
1005104523