Conserved expression and functions of PDE4 in rodent and human heart. - Wikidata - awgldk - TriplyDB

Conserved expression and functions of PDE4 in rodent and human heart.

Conserved expression and functions of PDE4 in rodent and human heart.

http://www.wikidata.org/entity/Q34548139

about

β1-adrenergic receptor antagonists signal via PDE4 translocation Phosphodiesterase 4D regulates baseline sarcoplasmic reticulum Ca2+ release and cardiac contractility, independently of L-type Ca2+ current Therapeutic potential of PDE modulation in treating heart disease Compartmentalization of β-adrenergic signals in cardiomyocytes Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice A compartmentalized mathematical model of the β1-adrenergic signaling system in mouse ventricular myocytes Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart Molecular inotropy mediated by cardiac miR-based PDE4D/PRKAR1α/phosphoprotein signaling Cardiac cyclic nucleotide phosphodiesterases: function, regulation, and therapeutic prospects.Chronic treatment with long acting phosphodiesterase-5 inhibitor tadalafil alters proteomic changes associated with cytoskeletal rearrangement and redox regulation in Type 2 diabetic hearts.Distinct patterns of constitutive phosphodiesterase activity in mouse sinoatrial node and atrial myocardium.Interventricular differences in β-adrenergic responses in the canine heart: role of phosphodiesterases.The upstream conserved regions (UCRs) mediate homo- and hetero-oligomerization of type 4 cyclic nucleotide phosphodiesterases (PDE4s).Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2.UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy.Cell-to-cell variability in troponin I phosphorylation in a porcine model of pacing-induced heart failure.Interaction between phosphodiesterases in the regulation of the cardiac β-adrenergic pathway.Compartmentalization of beta-adrenergic signals in cardiomyocytes.CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting.Spatial control of the βAR system in heart failure: the transverse tubule and beyond.PDE4B mediates local feedback regulation of β₁-adrenergic cAMP signaling in a sarcolemmal compartment of cardiac myocytes.Cardiac Adenylyl Cyclase and Phosphodiesterase Expression Profiles Vary by Age, Disease, and Chronic Phosphodiesterase Inhibitor Treatment.PDE3 inhibition in dilated cardiomyopathy.Compartmentation of cAMP signalling in cardiomyocytes in health and disease.Ca(2+)/calmodulin-activated phosphodiesterase 1A is highly expressed in rabbit cardiac sinoatrial nodal cells and regulates pacemaker function.Diminished responsiveness to dobutamine as an inotrope in mice with cecal ligation and puncture-induced sepsis: attribution to phosphodiesterase 4 upregulation.Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes.PDE4 in the human heart - major player or little helper?PDE3, but not PDE4, reduces β₁ - and β₂-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients.PDE2 activity differs in right and left rat ventricular myocardium and differentially regulates β2 adrenoceptor-mediated effects.Atropine augments cardiac contractility by inhibiting cAMP-specific phosphodiesterase type 4.Inhibiting Insulin-Mediated β2-Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac Dysfunction.Phosphodiesterase type 5 and cancers: progress and challenges.The PDE4 cAMP-Specific Phosphodiesterases: Targets for Drugs with Antidepressant and Memory-Enhancing Action.Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes.Functions of PDE3 Isoforms in Cardiac Muscle.Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain.Cardiomyocyte Membrane Structure and cAMP Compartmentation Produce Anatomical Variation in β2AR-cAMP Responsiveness in Murine Hearts.Roles of A-Kinase Anchoring Proteins and Phosphodiesterases in the Cardiovascular System.Chronic cardiac pressure overload induces adrenal medulla hypertrophy and increased catecholamine synthesis.

P2860

Q24313618-B848C53C-CEE7-43EB-92F4-998263987C89 Q24337525-F7D7FDA1-DB91-4531-9A3D-B5A9349657B3 Q27005761-AB27C57E-F399-4306-95B7-33F8CFBD4764 Q27026992-BB154EBD-713F-4D10-AF72-E071CCE2FFD0 Q28507989-A91E6869-16DA-4F1B-BBA8-3C98B0B11708 Q28540046-DE667385-0D27-4B06-A2E4-FD37D7CA6B58 Q28574432-520364C7-42E5-424B-AE98-E741B25E0809 Q30828261-6FCA9777-4FAB-4736-963D-F246904F11A1 Q33966155-105D333A-EE86-4F60-ADF1-244B6AB76947 Q34152435-5228331A-B9A7-406D-B179-052197002C39 Q34451028-48B84038-01B0-4A33-9A14-D216B7382D19 Q35021924-09B34883-8D71-4D75-A1C2-28D153D28567 Q35042655-D544CC5D-E6E1-4645-95A0-01ED65A28F65 Q35172592-AFAC9E17-569C-4375-81C2-3D43D27279CC Q35181565-0AB5B862-5419-4D46-AE4D-294A76E14A10 Q35898464-C72888CA-3110-4486-B071-B6902FA7D871 Q36270020-E5A4C858-F484-4D95-B45D-1C04F68E2E64 Q36384788-57E06D90-3113-4958-B228-C1C6C511B5D8 Q36385906-235063F6-CD30-4B1B-99F6-8D1C6CB150F5 Q36786520-643A52DD-5E54-48A5-9CE8-D35B4ABF39A3 Q37608719-ECD19630-B736-4EFE-9286-E9958DD2ACD2 Q37742299-68A926B2-296E-4BF1-A2F2-CDD1AE403F06 Q37941174-88EF0B5F-B1BF-47EA-A326-5FC0639C4FFD Q38079253-5A1FAAAF-9C73-4F93-86EC-B989EBA47765 Q38760680-7FCD2801-6928-4B60-8C3D-8411A7EC2CDC Q39156287-AB3C9257-30FB-453F-B316-F185B1B70AA8 Q41865256-C12C3D6C-D46A-466D-B29A-DF8A73041EC4 Q42155453-851180D7-1F14-46D9-8811-89D36068B45E Q42155457-43F360DB-1817-421D-8CEC-1F9BD00C55F3 Q42285592-BAD80AA8-A29F-4748-B25B-ED04F66B7B9B Q46039285-E7348B22-73CB-424F-900F-173A876B71FC Q46138106-28258F55-94BE-4223-A20D-753794F4C739 Q47171803-51104362-80F5-465A-A183-12DAE31659E9 Q47732733-50C03AE8-AF85-4E48-BBA1-75B631AB2650 Q49787366-5117568C-5095-46C4-8569-818B2899EE9B Q50132075-599C5730-440B-4D82-80FF-1C20D77080D5 Q52610098-E046946E-7E16-49CA-85CB-CCD99339FC19 Q52691050-C3FF3CB3-2F21-4E61-8FF6-B2497A79B256 Q52809588-A75D695B-56CD-4A68-A165-8D312ED0BA6F Q54592005-1053C07D-5391-49F1-B81C-691C8CABD2CB

P2860

Conserved expression and functions of PDE4 in rodent and human heart.

http://www.wikidata.org/entity/Q34548139

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Conserved expression and functions of PDE4 in rodent and human heart.

@ast

Conserved expression and functions of PDE4 in rodent and human heart.

@en

Conserved expression and functions of PDE4 in rodent and human heart.

@nl

type

label

Conserved expression and functions of PDE4 in rodent and human heart.

@ast

Conserved expression and functions of PDE4 in rodent and human heart.

@en

Conserved expression and functions of PDE4 in rodent and human heart.

@nl

prefLabel

Conserved expression and functions of PDE4 in rodent and human heart.

@ast

Conserved expression and functions of PDE4 in rodent and human heart.

@en

Conserved expression and functions of PDE4 in rodent and human heart.

@nl

P1433

Q34548139-744BFC28-3DBA-49EE-BD3C-182420FF243B

P1476

Q34548139-56A5DE6A-2791-47D8-AEA5-F43334ED1FF1

P2093

Q34548139-09335770-AA02-42BD-B195-2BDAD447B034

Q34548139-8063709B-1F16-45A5-AFB3-5BD3034B6BF2

Q34548139-8A2FF4B6-9064-477B-B5D6-3138DFBAE23F

Q34548139-99DAA9A1-2C1F-4861-B567-A6B293E8C492

Q34548139-D1E20488-87B7-4397-8078-51B7B484AE87

P2860

Q34548139-0022C585-B540-4DB5-A2D6-24F7F44C4F3B

Q34548139-0B6967CA-DBB7-4AC7-84F8-50F0537E913F

Q34548139-0C348260-232D-470A-922C-051B6E43BFB1

Q34548139-0EA389C5-9A81-4ECE-8503-2AD856A52BF7

Q34548139-0F788E6A-7AA5-449E-97A3-72BF25B3568F

Q34548139-10476F4E-83FB-4880-BA74-58052259284F

Q34548139-13EA96D7-4EDC-4D41-925F-F0C7A50522B9

Q34548139-14679AC9-7B44-4A2B-9254-F33801028771

Q34548139-16B8E637-4EA8-4D57-AA26-AF6390160BA9

Q34548139-17E250C1-68FE-43FE-8114-D6414991A74B

P2888

Q34548139-4FFBE228-7307-4BFA-81B6-58908099A866

P304

Q34548139-8C1F5A79-7C00-48A6-AF67-B3EF64CFD53C

P31

Q34548139-DA0615D5-9A55-4E7A-BE98-26C842669EBC

P356

Q34548139-4314136F-3735-4865-904F-2D657B85294E

P433

Q34548139-C20A5FFB-1714-43DE-9D2D-180777BD74BB

P478

Q34548139-C98C5DBA-0715-45FA-B0D8-2FD6DB3E0645

P50

Q34548139-941EE5A2-E733-4226-961F-4F061CA05042

P577

Q34548139-A4C95FB0-1227-410C-937D-CFBA7DA44573

P5875

Q34548139-0A0E0B49-2016-4223-8809-247807229273

P6179

Q34548139-DEBDB0AC-AF7A-4741-9724-6818964153D1

P698

Q34548139-E0B40661-9D78-4CAE-98D0-58F27803F7EE

P932

Q34548139-E060DAB8-3322-40BD-A3FA-B5D1113D9C8D

P356

S00395-010-0138-8

P1433

Basic Research in Cardiology

P1476

Conserved expression and functions of PDE4 in rodent and human heart.

@en

P2093

Colleen Scheitrum

http://www.w3.org/2001/XMLSchema#string

Judith Krall

http://www.w3.org/2001/XMLSchema#string

Marco Conti

http://www.w3.org/2001/XMLSchema#string

Matthew A Movsesian

http://www.w3.org/2001/XMLSchema#string

Moses Xie

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic amp-specific phosphodiesterase PDE4A10

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine

Keynote review: phosphodiesterase-4 as a therapeutic target

Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart

Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure

Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4

Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling

P2888

s00395-010-0138-8

P304

249-262

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S00395-010-0138-8

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

106

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-12-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49686273

http://www.w3.org/2001/XMLSchema#string

P6179

1051041058

http://www.w3.org/2001/XMLSchema#string

P698

21161247

http://www.w3.org/2001/XMLSchema#string

P932

3032896

http://www.w3.org/2001/XMLSchema#string