Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
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The 8 and 5 kDa fragments of plasma gelsolin form amyloid fibrils by a nucleated polymerization mechanism, while the 68 kDa fragment is not amyloidogenicA Nanobody Binding to Non-Amyloidogenic Regions of the Protein Human Lysozyme Enhances Partial Unfolding but Inhibits Amyloid Fibril FormationAmyloidogenic regions and interaction surfaces overlap in globular proteins related to conformational diseases.Consistent picture of the reversible thermal unfolding of hen egg-white lysozyme from experiment and molecular dynamicsLarge proteins have a great tendency to aggregate but a low propensity to form amyloid fibrilsLocal cooperativity in an amyloidogenic state of human lysozyme observed at atomic resolution.Effect of mid-infrared free-electron laser irradiation on refolding of amyloid-like fibrils of lysozyme into native formAnalysis of the native structure, stability and aggregation of biotinylated human lysozyme.Covalent α-synuclein dimers: chemico-physical and aggregation properties.Serine protease HtrA1 accumulates in corneal transforming growth factor beta induced protein (TGFBIp) amyloid depositsMid-infrared free-electron laser tuned to the amide I band for converting insoluble amyloid-like protein fibrils into the soluble monomeric formHighly amyloidogenic two-chain peptide fragments are released upon partial digestion of insulin with pepsin.Dissecting structure of prion amyloid fibrils by hydrogen-deuterium exchange ultraviolet Raman spectroscopy.Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy.Amyloid protofibrils of lysozyme nucleate and grow via oligomer fusion.Intrinsically semi-disordered state and its role in induced folding and protein aggregation"Native-like aggregation" of the acylphosphatase from Sulfolobus solfataricus and its biological implications.Disulfide bonds reduce the toxicity of the amyloid fibrils formed by an extracellular protein.Effects of hesperidin, a flavanone glycoside interaction on the conformation, stability, and aggregation of lysozyme: multispectroscopic and molecular dynamic simulation studies?Syntheses and structure-activity relationships of seven manganese-salen derivatives as anti-amyloidogenic and fibril-destabilizing agents against hen egg-white lysozyme aggregation.Amyloidogenic sequences in native protein structures.Multisite aggregation of p53 and implications for drug rescue.Characterizing intermolecular interactions that initiate native-like protein aggregation.Lysozyme Mutants Accumulate in Cells while Associated at their N-terminal Alpha-domain with the Endoplasmic Reticulum Chaperone GRP78/BiP.Population of nonnative states of lysozyme variants drives amyloid fibril formation.Two latent and two hyperstable polymeric forms of human neuroserpin.The mechanism of fibril formation of a non-inhibitory serpin ovalbumin revealed by the identification of amyloidogenic core regions.Inhibition of HEWL fibril formation by taxifolin: Mechanism of action.The Significance of the Location of Mutations for the Native-State Dynamics of Human Lysozyme.FoldAmyloid: a method of prediction of amyloidogenic regions from protein sequence.On the molecular structure of human neuroserpin polymers.Molecular dynamics simulations of lysozyme-lipid systems: probing the early steps of protein aggregation.Circular dichroism and electron microscopy studies in vitro of 33-mer gliadin peptide revealed secondary structure transition and supramolecular organization.Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates.Lysozyme interaction with negatively charged lipid bilayers: protein aggregation and membrane fusion
P2860
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P2860
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@ast
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@en
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@nl
type
label
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@ast
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@en
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@nl
prefLabel
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@ast
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@en
Identification of the core structure of lysozyme amyloid fibrils by proteolysis.
@nl
P2093
P1476
Identification of the core structure of lysozyme amyloid fibrils by proteolysis
@en
P2093
Christopher M Dobson
Erica Frare
Mireille Dumoulin
Patrizia Polverino de Laureto
P304
P356
10.1016/J.JMB.2006.06.055
P407
P577
2006-07-07T00:00:00Z