Physicochemical selectivity of the BBB microenvironment governing passive diffusion--matching with a porcine brain lipid extract artificial membrane permeability model.

Physicochemical selectivity of the BBB microenvironment governing passive diffusion--matching with a porcine brain lipid extract artificial membrane permeability model.

Item
http://www.wikidata.org/entity/Q34556508
Challenges of using in vitro data for modeling P-glycoprotein efflux in the blood-brain barrier.Significance of lipid composition in a blood-brain barrier-mimetic PAMPA assay.A method to predict blood-brain barrier permeability of drug-like compounds using molecular dynamics simulationsA new in situ brain perfusion flow correction method for lipophilic drugs based on the pH-dependent Crone-Renkin equation.Physiologically based pharmacokinetic modelling of drug penetration across the blood-brain barrier--towards a mechanistic IVIVE-based approachFull efficacy with no CNS side-effects: unachievable panacea or reality? DMPK considerations in design of drugs with limited brain penetration.Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling.Improving the prediction of drug disposition in the brain.Blood-brain barrier structure and function and the challenges for CNS drug delivery.Predicting apparent passive permeability of Caco-2 and MDCK cell-monolayers: A mechanistic model.In-vitro evaluation of the P-glycoprotein interactions of a series of potentially CNS-active Amaryllidaceae alkaloids.Benzylphenylpyrrolizinones with Anti-amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment.
P2860

Physicochemical selectivity of the BBB microenvironment governing passive diffusion--matching with a porcine brain lipid extract artificial membrane permeability model.

Item
http://www.wikidata.org/entity/Q34556508
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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Physicochemical selectivity of ...... l membrane permeability model.
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P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932