Trabectedin (ET-743, Yondelis) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype.
about
Marine Natural Products as Models to Circumvent Multidrug ResistanceTrabectedin for the management of soft-tissue sarcoma.Down-regulation of the nucleotide excision repair gene XPG as a new mechanism of drug resistance in human and murine cancer cellsModulation of trabectedin (ET-743) hepatobiliary disposition by multidrug resistance-associated proteins (Mrps) may prevent hepatotoxicityWide-spectrum characterization of trabectedin: biology, clinical activity and future perspectives.Irreversible hepatotoxicity after administration of trabectedin to a pleiomorphic sarcoma patient with a rare ABCC2 polymorphism: a case report.Ecteinascidins. A review of the chemistry, biology and clinical utility of potent tetrahydroisoquinoline antitumor antibiotics.
P2860
Q26741330-A072A378-812A-4214-90AD-F2B53FAB6185Q33384836-C90F031D-DEE4-4E0F-9681-938E13B2939BQ34202863-155BF5A0-D00B-4F9B-9815-C6D306315514Q36948681-C7762CF8-D8C2-44B4-BD7F-32334428BE2BQ37760957-78FC5A2B-0BAB-4470-8177-5DAA9C8C2837Q38136298-CE7F6111-F63F-4A83-AAD0-ECD6FCEA7522Q38255906-661A6D4B-F409-4451-A815-7C15A32FD355
P2860
Trabectedin (ET-743, Yondelis) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype.
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@ast
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@en
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@nl
type
label
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@ast
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@en
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@nl
prefLabel
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@ast
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@en
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@nl
P2093
P1476
Trabectedin (ET-743, Yondelis) ...... ultidrug resistance phenotype.
@en
P2093
Jan H M Schellens
Jan-Hendrik Beumer
Jos H Beijnen
Luis Lopez-Lazaro
Mariet Ouwehand
Niels E F Franke
Olaf van Tellingen
P2860
P2888
P356
10.1007/S10637-006-7773-9
P50
P577
2007-02-01T00:00:00Z
P6179
1048904040