The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells.
about
Distinct cytoplasmic and nuclear functions of the stress induced protein DDIT3/CHOP/GADD153FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E.The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma culturesNuclear expression of FLT1 and its ligand PGF in FUS-DDIT3 carrying myxoid liposarcomas suggests the existence of an intracrine signaling loop.Cell senescence in myxoid/round cell liposarcomaAnimal models of soft-tissue sarcoma.PPARγ agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcomaAdvances in the targeted therapy of liposarcoma.Normal and functional TP53 in genetically stable myxoid/round cell liposarcoma.Adult human sarcomas. I. Basic science.DDIT3 Expression in Liposarcoma Development.Global preamplification simplifies targeted mRNA quantification.Liposarcoma: molecular genetics and therapeutics.Modeling sarcomagenesis using multipotent mesenchymal stem cells.The diversity of soft tissue tumours with EWSR1 gene rearrangements: a review.FUS-CHOP fusion protein expression coupled to p53 deficiency induces liposarcoma in mouse but not in human adipose-derived mesenchymal stem/stromal cells.Regulatory mechanisms, expression levels and proliferation effects of the FUS-DDIT3 fusion oncogene in liposarcoma.A mechanistic study on the metastasis inducing function of FUS-CHOP fusion protein in liposarcoma.Expression of FUS-CHOP fusion protein in immortalized/transformed human mesenchymal stem cells drives mixoid liposarcoma formation.Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and casein kinase II inhibition as a potential treatment option.Sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines.The Scandinavian Sarcoma Group: 30 years' experience.Impact of Heat Shock Protein A 12B Overexpression on Spinal Astrocyte Survival Against Oxygen-Glucose-Serum Deprivation/Restoration in Primary Cultured Astrocytes.Analysis of expression profile data identifies key genes and pathways in hepatocellular carcinoma.Identification of inhibitors regulating cell proliferation and FUS-DDIT3 expression in myxoid liposarcoma using combined DNA, mRNA, and protein analyses.
P2860
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P2860
The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@ast
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@en
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@nl
type
label
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@ast
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@en
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@nl
prefLabel
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@ast
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@en
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@nl
P2093
P2860
P4510
P1476
The myxoid/round cell liposarc ...... cted human fibrosarcoma cells.
@en
P2093
Anita Olofsson
Carola Andersson
Christina Kåbjörn-Gustafsson
Elisabeth Warnhammar
Helena Willén
Katarina Engström
Marita Olsson
Melker Göransson
Sofia Järnum
P2860
P304
P356
10.2353/AJPATH.2006.050872
P407
P50
P577
2006-05-01T00:00:00Z