HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
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HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZMultifaceted functions and roles of HBZ in HTLV-1 pathogenesisHistorical review of the causes of cancerThe Role of HBZ in HTLV-1-Induced OncogenesisRoles of HTLV-1 basic Zip Factor (HBZ) in Viral Chronicity and Leukemic Transformation. Potential New Therapeutic Approaches to Prevent and Treat HTLV-1-Related DiseasesFrom Immunodeficiency to Humanization: The Contribution of Mouse Models to Explore HTLV-1 LeukemogenesisHow does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON target or OFF target effects?Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virusNovel interactions between the HTLV antisense proteins HBZ and APH-2 and the NFAR protein family: Implications for the HTLV lifecyclesEpigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs.Regulation of human T-lymphotropic virus type I latency and reactivation by HBZ and Rex.Characterization of simian T-cell leukemia virus type 1 in naturally infected Japanese macaques as a model of HTLV-1 infection.Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis.Human T-cell leukemia virus type 3 (HTLV-3) and HTLV-4 antisense-transcript-encoded proteins interact and transactivate Jun family-dependent transcription via their atypical bZIP motifThe transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.Animal Models Utilized in HTLV-1 ResearchHBZ stimulates brain-derived neurotrophic factor/TrkB autocrine/paracrine signaling to promote survival of human T-cell leukemia virus type 1-Infected T cellsHTLV-1-infected CD4+ T-cells display alternative exon usages that culminate in adult T-cell leukemiaHTLV-1 bZIP factor induces inflammation through labile Foxp3 expression.Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisHTLV-1 bZIP factor enhances TGF-β signaling through p300 coactivator.Making sense out of antisense transcription in human T-cell lymphotropic viruses (HTLVs).Molecular determinants of human T-lymphotropic virus type 1 transmission and spread.Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease.Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells.HTLV-2 APH-2 expression is correlated with proviral load but APH-2 does not promote lymphocytosis.HTLV-1 bZIP factor impairs cell-mediated immunity by suppressing production of Th1 cytokines.Interferon-γ Promotes Inflammation and Development of T-Cell Lymphoma in HTLV-1 bZIP Factor Transgenic Mice.Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATLHTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cellsThe HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP.HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals.Human T-cell leukemia virus type 2 antisense viral protein 2 is dispensable for in vitro immortalization but functions to repress early virus replication in vivo.Foxp3-dependent transformation of human primary CD4+ T lymphocytes by the retroviral protein taxHTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory ReceptorsTumor necrosis factor alpha inhibitors have no effect on a human T-lymphotropic virus type-I (HTLV-I)-infected cell line from patients with HTLV-I-associated myelopathy.Immunopathogenesis of human T-cell leukemia virus type-1-associated myelopathy/tropical spastic paraparesis: recent perspectives
P2860
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P2860
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@ast
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@en
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@nl
type
label
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@ast
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@en
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@nl
prefLabel
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@ast
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@en
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@nl
P2093
P2860
P50
P1433
P1476
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
@en
P2093
Kei Shimizu
Koichi Ohshima
Mika Yoshida
Naganari Ohkura
Paola Miyazato
Patrick L Green
Shimon Sakaguchi
Tiejun Zhao
Tomoyuki Yamaguchi
P2860
P304
P356
10.1371/JOURNAL.PPAT.1001274
P577
2011-02-10T00:00:00Z