Isoflurane neurotoxicity is mediated by p75NTR-RhoA activation and actin depolymerization. - Wikidata - awgldk - TriplyDB

Isoflurane neurotoxicity is mediated by p75NTR-RhoA activation and actin depolymerization.

Isoflurane neurotoxicity is mediated by p75NTR-RhoA activation and actin depolymerization.

http://www.wikidata.org/entity/Q34569944

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Early Exposure to General Anesthesia Disrupts Spatial Organization of Presynaptic Vesicles in Nerve Terminals of the Developing Rat Subiculum.Functional implications of an early exposure to general anesthesia: are we changing the behavior of our children?Early exposure to general anesthesia disturbs mitochondrial fission and fusion in the developing rat brain Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.Developmental disability in the young and postoperative cognitive dysfunction in the elderly after anesthesia and surgery: do data justify changing clinical practice?Neuraxial analgesia in neonates and infants: a review of clinical and preclinical strategies for the development of safety and efficacy data.Positron Emission Tomography with [(18)F]FLT Revealed Sevoflurane-Induced Inhibition of Neural Progenitor Cell Expansion in vivo.The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.Neuron-targeted caveolin-1 protein enhances signaling and promotes arborization of primary neurons.Isoflurane protects against human endothelial cell apoptosis by inducing sphingosine kinase-1 via ERK MAPK.Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation.Astrocytes Protect against Isoflurane Neurotoxicity by Buffering pro-brain-derived Neurotrophic Factor Single sevoflurane exposure decreases neuronal nitric oxide synthase levels in the hippocampus of developing rats Mechanistic insights into neurotoxicity induced by anesthetics in the developing brain.Neuropathological sequelae of developmental exposure to antiepileptic and anesthetic drugs.Feasibility and pilot study of the Pediatric Anesthesia NeuroDevelopment Assessment (PANDA) project Anesthetics interfere with the polarization of developing cortical neurons.Preclinical research into the effects of anesthetics on the developing brain: promises and pitfalls Anesthetics interfere with axon guidance in developing mouse neocortical neurons in vitro via a γ-aminobutyric acid type A receptor mechanism.The mitochondrial division inhibitor Mdivi-1 rescues mammalian neurons from anesthetic-induced cytotoxicity Isoflurane affects the cytoskeleton but not survival, proliferation, or synaptogenic properties of rat astrocytes in vitro.The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury.Anesthetic Sevoflurane Causes Rho-Dependent Filopodial Shortening in Mouse Neurons MicroRNA-34c is regulated by p53 and is involved in sevoflurane-induced apoptosis in the developing rat brain potentially via the mitochondrial pathway General anaesthetics and the developing brain: an overview.Resolving the contributions of anaesthesia, surgery, and nerve injury on brain derived neurotrophic factor expression in the medial prefrontal cortex of male rats in the CCI model of neuropathic pain.Molecular Mechanisms of Anesthetic Neurotoxicity: A Review of the Current Literature.Lasting impact of general anaesthesia on the brain: mechanisms and relevance.VGF (TLQP-62)-induced neurogenesis targets early phase neural progenitor cells in the adult hippocampus and requires glutamate and BDNF signaling.Sevoflurane Impairs Growth Cone Motility in Dissociated Murine Neurons.Tissue plasminogen activator (tPA) attenuates propofol-induced apoptosis in developing hippocampal neurons.Dexmedetomidine mitigates isoflurane-induced neurodegeneration in fetal rats during the second trimester of pregnancy.Isoflurane post-treatment ameliorates GMH-induced brain injury in neonatal rats.Inhibiting Rho kinase 2 reduces memory dysfunction in adult rats exposed to sevoflurane at postnatal days 7-9.Neuronal vulnerability to anesthesia neurotoxicity depends on age of neurons.Sevoflurane exposure in postnatal rats induced long-term cognitive impairment through upregulating caspase-3/cleaved-poly (ADP-ribose) polymerase pathway.[Anesthesia-induced neurotoxicity: statement of the scientific working groups for pediatric anesthesia and neuroanesthesia].Isoflurane-induced inactivation of CREB through histone deacetylase 4 is responsible for cognitive impairment in developing brain.Isoflurane decreases proliferation and differentiation, but none of the effects persist in human embryonic stem cell-derived neural progenitor cells.Genetic and pharmacological intervention of the p75NTR pathway alters morphological and behavioural recovery following traumatic brain injury in mice.

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P2860

Isoflurane neurotoxicity is mediated by p75NTR-RhoA activation and actin depolymerization.

http://www.wikidata.org/entity/Q34569944

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2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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Isoflurane neurotoxicity is me ...... on and actin depolymerization.

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Isoflurane neurotoxicity is me ...... on and actin depolymerization.

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Isoflurane neurotoxicity is me ...... on and actin depolymerization.

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Isoflurane neurotoxicity is me ...... on and actin depolymerization.

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Isoflurane neurotoxicity is me ...... on and actin depolymerization.

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Isoflurane neurotoxicity is me ...... on and actin depolymerization.

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Isoflurane neurotoxicity is me ...... on and actin depolymerization.

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Brian P Lemkuil

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Hemal H Patel

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John C Drummond

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Matthew L Pearn

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P2860

Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system

A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis

Rho GTPases in cell biology

Regulation of cell survival by secreted proneurotrophins.

The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI.

Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

General anesthesia activates BDNF-dependent neuroapoptosis in the developing rat brain

Phenylalanine activates the mitochondria-mediated apoptosis through the RhoA/Rho-associated kinase pathway in cortical neurons

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

Rho GTPases in neuronal morphogenesis

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