Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
about
A unified model of the GABA(A) receptor comprising agonist and benzodiazepine binding sitesDiazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligandsStructural mechanisms underlying benzodiazepine modulation of the GABA(A) receptorPregabalin for the Treatment of Drug and Alcohol Withdrawal Symptoms: A Comprehensive ReviewStudying Cerebellar Circuits by Remote Control of Selected Neuronal Types with GABA(A) ReceptorsRisk of fractures requiring hospitalization after an initial prescription for zolpidem, alprazolam, lorazepam, or diazepam in older adults.Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variabilityFrom synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors.Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABAA receptors: evidence of a novel benzodiazepine site in the α1-α1 interface.GABA(A) receptors in normal development and seizures: friends or foes?Colchicine: a novel positive allosteric modulator of the human 5-hydroxytryptamine3A receptorStructural rearrangements in loop F of the GABA receptor signal ligand binding, not channel activation.The role of Loop F in the activation of the GABA receptor.Zolpidem, a clinical hypnotic that affects electronic transfer, alters synaptic activity through potential GABA receptors in the nervous system without significant free radical generation.A new sublingual formulation of zolpidem for the treatment of sleep-onset insomnia.Probing the orthosteric binding site of GABAA receptors with heterocyclic GABA carboxylic acid bioisosteres.The behavioral pharmacology of zolpidem: evidence for the functional significance of α1-containing GABA(A) receptors.Mechanism of Allosteric Modulation of the Cys-loop Receptors.Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are differentThe Association Between the Use of Zolpidem and the Risk of Alzheimer's Disease Among Older People.The F-loop of the GABA A receptor gamma2 subunit contributes to benzodiazepine modulation.Docking of 1,4-benzodiazepines in the alpha1/gamma2 GABA(A) receptor modulator site.Effects of zolpidem on sedation, anxiety, and memory in the plus-maze discriminative avoidance task.What is the effective component in suanzaoren decoction for curing insomnia? Discovery by virtual screening and molecular dynamic simulation.Sedative and anticonvulsant effects of zolpidem in adult and aged mice.Some insights into the binding mechanism of the GABAA receptor: a combined docking and MM-GBSA study.The role of loops B and C in determining the potentiation of GABA receptors by midazolam
P2860
Q21559651-26B11770-31D7-43D7-A12E-AA1893A00ADCQ24610075-E5B167AF-0E97-4A2C-A99C-E5D8980C5D6BQ24645323-A2757FB8-CB7A-42FA-922C-7A59A0837855Q28074617-80E7C9A3-FB5E-407A-9D84-BF00879FFDB5Q30483976-60CAC472-FDC5-4902-8042-D0D6DBDCF8F2Q34233363-45D8EA79-06D9-4F7B-8E1E-71393FFFB24FQ34574831-58E2657E-5D49-4DE6-8092-EE25A5D73C18Q36166392-DF1431AC-7294-4076-8C8E-1D2E9B6BB204Q37040099-372A6015-302E-4AC0-ACB0-4F6F715A9254Q37104140-D488C646-02B5-488C-97D5-22C69BA60FE2Q37168493-D59B90E6-4971-4430-82F2-D292BEEBDF5DQ37260237-4FE0073D-1B22-4253-852E-91FE66A7D64AQ37666299-458555E5-C40D-4D0D-811A-57CBA121FE8DQ37666650-1E80D9C3-39B6-4612-B634-35BFC5C72AEAQ37979871-9CC5A4B3-3B8F-4B2B-987D-995BBE18DCB6Q38173266-D95091F4-30F9-4067-8056-50DC587C6B13Q38190472-90441C6D-374A-4718-B702-E2C35061F334Q38974419-CE9FD4A3-A607-4602-A652-F8A3F6918558Q39923376-8EBCA487-AF07-456A-934D-AAABB54A0541Q40051486-5101CEB6-549D-4872-AD2B-C153FAC6629EQ40059375-F8A990EF-3717-465C-9D82-B23E983EABD6Q42147480-E86EC991-8BE3-4FFA-A850-25790EFEE887Q44931603-1305B56D-6D35-4BFF-8995-E55E1A83492AQ46556621-DAA1121B-0491-4386-88FF-C88A7A0F2A17Q46793491-0A319541-15CF-4CDC-AB60-16B44152CC47Q53670140-AA933A6B-B0E8-478B-B4AA-3F8A4978D004Q59136162-5561CF21-0D70-4930-BAA1-3A53C361B7D8
P2860
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@ast
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@en
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@nl
type
label
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@ast
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@en
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@nl
prefLabel
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@ast
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@en
Structural determinants for high-affinity zolpidem binding to GABA-A receptors.
@nl
P2093
P356
P1476
Structural determinants for high-affinity zolpidem binding to GABA-A receptors
@en
P2093
Amy M Kucken
Cynthia Czajkowski
Feyza Sancar
Jeremy A Teissére
P356
10.1124/MOL.106.029595
P577
2006-09-29T00:00:00Z