Design and synthesis of compounds that extend yeast replicative lifespan. - Wikidata - awgldk - TriplyDB

Design and synthesis of compounds that extend yeast replicative lifespan.

Design and synthesis of compounds that extend yeast replicative lifespan.

http://www.wikidata.org/entity/Q34573125

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Interactomic and pharmacological insights on human sirt-1 Biochemical effects of SIRT1 activators SIRT1 and Kidney Function Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.Small-molecule allosteric activators of sirtuins.Sirt3, mitochondrial ROS, ageing, and carcinogenesis.Resveratrol and life extension.Aging biology: a new frontier for drug discovery.dSir2 and longevity in Drosophila.A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers.Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals Calorie restriction: what recent results suggest for the future of ageing research DNA damage and ageing: new-age ideas for an age-old problem Sirtuins and their relevance to the kidney.Using mitochondrial sirtuins as drug targets: disease implications and available compounds.Diet and aging.Compounds that confer thermal stress resistance and extended lifespan.Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore.In vitro and in vivo evaluation of resveratrol and 3,5-dihydroxy-4'-acetoxy-trans-stilbene in the treatment of human prostate carcinoma and melanoma.Autophagy and mitochondrial dysfunction in adjuvant-arthritis rats treatment with resveratrol.Induction of a reversible, non-cytotoxic S-phase delay by resveratrol: implications for a mechanism of lifespan prolongation and cancer protection.Resveratrol: why is it a promising therapy for chronic kidney disease patients?Resveratrol, sirtuins, and the promise of a DR mimetic.Dietary lipophilic antioxidants: implications and significance in the aging process.Epigenetic effects of natural polyphenols: a focus on SIRT1-mediated mechanisms.Resveratrol and diabetes During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent.The effect of resveratrol and its methylthio-derivatives on EGFR and Stat3 activation in human HaCaT and A431 cells.Anticancer Activity of Stilbene-Based Derivatives.Impact of caloric restriction on myocardial ischaemia/reperfusion injury and new therapeutic options to mimic its effects SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis.Dietary Resveratrol Does Not Affect Life Span, Body Composition, Stress Response, and Longevity-Related Gene Expression in Drosophila melanogaster.The role of calcium channel blockers and resveratrol in the prevention of paraquat-induced parkinsonism in Drosophila melanogaster: a locomotor analysis.Lipase catalyzed acetylation of 3,5,4'-trihydroxystilbene: optimization and kinetics study

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Design and synthesis of compounds that extend yeast replicative lifespan.

http://www.wikidata.org/entity/Q34573125

description

2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Design and synthesis of compounds that extend yeast replicative lifespan.

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Design and synthesis of compounds that extend yeast replicative lifespan.

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Design and synthesis of compounds that extend yeast replicative lifespan.

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type

label

Design and synthesis of compounds that extend yeast replicative lifespan.

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Design and synthesis of compounds that extend yeast replicative lifespan.

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Design and synthesis of compounds that extend yeast replicative lifespan.

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prefLabel

Design and synthesis of compounds that extend yeast replicative lifespan.

@ast

Design and synthesis of compounds that extend yeast replicative lifespan.

@en

Design and synthesis of compounds that extend yeast replicative lifespan.

@nl

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J.1474-9726.2006.00259.X

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Design and synthesis of compounds that extend yeast replicative lifespan.

@en

P2093

Allen Chen

http://www.w3.org/2001/XMLSchema#string

Anne Kisielewski

http://www.w3.org/2001/XMLSchema#string

Christine Miller

http://www.w3.org/2001/XMLSchema#string

Hongying Yang

http://www.w3.org/2001/XMLSchema#string

Jeffrey K Adams

http://www.w3.org/2001/XMLSchema#string

Konrad T Howitz

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Robert E Zipkin

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P2860

Sir2-independent life span extension by calorie restriction in yeast

Structure of the histone deacetylase SIRT2

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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